arXiv:2606.18640cs.LGq-bio.QM2026-06

构建多模态糖尿病血糖预测基准,助力算法公平对比与创新

MetaboNet-Bench: A Multi-modal Benchmark for Glucose Forecasting in Type 1 Diabetes

论文配图:MetaboNet-Bench: A Multi-modal Benchmark for Glucose Forecasting in Type 1 Diabetes
图 1 · 摘自论文原文
  • 基于血糖、胰岛素、碳水数据构建多模态预测基准框架
  • 验证多模态数据提升效果依赖模型复杂度,非简单线性增益
  • 适合糖尿病研究者、医疗AI开发者使用,推动临床可落地模型发展

血糖预测算法是1型糖尿病血糖管理的关键。当前研究虽已提出众多算法,但缺乏标准化评估基准,导致模型比较困难且阻碍创新。此外,多数算法仅依赖连续血糖监测(CGM)数据,忽略胰岛素剂量和碳水摄入等多模态信号。为此,我们提出MetaboNet-Bench,一个面向1型糖尿病患者的多模态血糖预测基准,提供开源可扩展的评估框架,支持融合血糖、胰岛素与碳水数据的算法对比。通过评估多个近期发布的预测模型及自研多模态时序模型,结果表明:多模态数据的增益取决于模型复杂度;引入更多临床指标有助于识别未来研究的关键空白。

原文摘要 · Abstract (English)

Glucose forecasting algorithms are an important aspect of glycemic control management in type 1 diabetes. So far, the research community has developed numerous algorithms and models for forecasting. However, it is well-recognized that the lack of standardized model performance evaluation benchmarks makes fair comparison difficult and hinders further innovation, and thus benchmark standardization is in urgent need. Furthermore, many published glucose forecasting algorithms are limited to CGM data alone, ignoring other multimodal signals such as insulin dosing and carbohydrate intake. Here, we introduce MetaboNet-Bench, a benchmark for multimodal glucose forecasting for patients with type 1 diabetes that provides an extensible open-source evaluation framework for comparison of glucose forecasting algorithms that leverage glucose, insulin, and carbohydrate data. We then demonstrate its utility by benchmarking several recently published glucose forecasting models and a custom multimodal time-series model, representing different model architectures. The results show that the benefit of adding data modalities is conditioned on the complexity of the model and that incorporating more clinical metrics helps identify meaningful gaps to fill for future research.

血糖预测多模态糖尿病时间序列

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