提出几何约束网络GeoCat,提升冠脉超声血管边界分割的临床准确性。
Clinically Aligned Geometry Constraints for Robust IVUS Vessel Boundary Segmentation

- 双坐标编码+跨域注意力,融合时序信息增强边界定位
- 95%边界距离降至0.14毫米,拓扑错误率仅1.0%
- 精准还原血管直径与角度,适合临床斑块定量分析
血管内超声(IVUS)腔内和外弹力膜(EEM)分割对定量评估冠状动脉斑块负荷至关重要。传统方法注重重叠率,常出现边界漂移和拓扑错误,影响斑块面积、斑块负担及几何测量。本文提出GeoCat,一种几何一致性网络,处理5帧IVUS序列,采用双笛卡尔-极坐标编码器与跨域注意力机制及时间融合。通过可微分几何一致性损失,直接监督直径、方向和截面面积等临床相关描述符。模型在146名患者共12,242帧标注数据上训练,覆盖两种商用系统。评估涵盖分割精度与斑块相关临床指标:Dice/IoU、边界度量(95HD(mm)、ASSD)、拓扑违反率,以及临床几何误差(dmax/dmin、角度、面积)。实验结果表明,GeoCat实现Dice为0.93,95HD降低至0.14毫米,拓扑违规率降至1.0%。关键改进在于几何保真度:直径误差0.13–0.16毫米,角度误差约8度,支持可靠斑块负荷量化。
原文摘要 · Abstract (English)
Intravascular ultrasound (IVUS) lumen and external elastic membrane (EEM) segmentation is important for quantitative coronary plaque burden assessment. Errors in lumen or EEM delineation directly propagate to plaque area, plaque burden and geometric measurements. However, standard methods prioritising overlap scores often suffer from boundary drift and topology errors, leading to inaccurate clinical measurements. We present GeoCat, a geometry-consistent network that processes 5-frame IVUS clips using dual Cartesian-polar encoders with cross-domain attention and temporal fusion. A differentiable geometry consistency loss directly supervises clinically relevant descriptors including diameters, orientations, and cross-sectional areas. The model is trained on 12,242 annotated frames from 146 patients acquired with two commercial IVUS systems. We evaluate performance using both segmentation accuracy and plaque-relevant clinical metrics, including Dice/IoU, boundary measures(95HD (mm), ASSD), topology violation rate, and clinical geometry errors (dmax/dmin, angles, and areas). On our dataset, GeoCat achieves a Dice of 0.93, reduces 95HD to 0.14 mm, and lowers topology violations to 1.0%. Importantly, it significantly improves geometric fidelity, yielding diameter errors of 0.13-0.16 mm and angular errors of ~8 degrees, supporting reliable plaque burden quantification.
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