用少量标注数据,让AI精准判断前列腺MRI图像质量
Bridging Single Distortion Artifacts and Multifactorial Clinical Quality: Few-shot Biparametric MRI Quality Assessment via Distortion-trained Prototypical Networks

- 用双分支3D ResNet融合解剖与失真特征,区分真实结构与伪影
- 仅需5个样本即可准确预测复杂临床评分,对低质量图像识别率超87%
- 适合需要高效、标准化影像质控的临床医生和科研团队
临床前列腺多参数MRI高度依赖高质量扩散加权成像(DWI),但常因直肠气体导致几何失真,影响判读。尽管PI-QUAL评分系统逐渐成为标准,其主观性强、耗时且存在类别不平衡问题——低质量案例多样且稀少。以PRIME临床试验为例,6%的图像PI-QUAL评分低于4分,87%的DWI问题源于失真,其他临床质量问题更难获取。为应对标注数据双重稀缺,本文提出一种少样本双参数原型网络,用于自动化图像质量评估(IQA)。框架采用双分支3D ResNet融合T2WI与DWI特征,提供解剖上下文以区分真实形态与失真;引入特征线性调制(FiLM)与梯度反向层(GRL),在不同b值条件下对齐特征分布并抑制采集偏差。实验表明,仅用客观易得的失真标签进行元训练,模型可仅凭五个代表性样本有效适配复杂多因素临床评分(如PI-QUAL)。在两个数据集上的结果均显著优于现有少样本学习基线,为临床前列腺MRI质量控制提供了高效可行的解决方案。
原文摘要 · Abstract (English)
Clinical prostate multi-parametric MRI relies heavily on high-quality diffusion-weighted imaging (DWI), yet reading DWI is frequently compromised by geometric distortion, often caused by rectal air. Assessing quality via the PI-QUAL scoring system is an emerging clinical standard, but it is subjective, time-consuming and suffers from a class imbalance where low-quality cases are diverse and relatively scarce. Using the PRIME clinical trial as an example, there are $6\%$ images with PI-QUAL scores lower than 4, $87\%$ of DWI issues are due to distortion. Many of the other clinical quality issues are under-represented. To address this common dual-scarcity of annotated clinical data, we propose a few-shot biparametric prototypical network for automated image quality assessment (IQA). Our framework utilizes a dual-branch 3D ResNet to fuse T2-weighted and DWI features, providing anatomical context to distinguish true morphology from distortion. To handle real-world heterogeneity, we introduce feature-wise linear modulation (FiLM) and a gradient reversal layer (GRL) to align feature distributions conditioned on varying b-values while suppressing acquisition-related biases. We demonstrate that a model meta-trained solely on comparatively objective, readily obtainable distortion labels can effectively adapt to predicting complex, multi-factorial clinical quality scores such as PI-QUAL using only five representative samples. Experimental results on two datasets show that our method significantly outperforms few-shot learning baselines for this challenging IQA task, offering a practically feasible and data-efficient solution for standardizing prostate MRI quality control in clinical workflows.
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