无需全采样数据,用自学习分区提升多对比MRI重建质量。
Optimized Multi-Contrast Self-Supervised MRI Reconstruction using Learned k-space Partitioning
- 多对比图像联合训练,自动学习最优k空间分割方式。
- 在两个公开数据集上重建精度优于单对比自监督方法。
- 适合追求高保真度与加速成像的医学影像研究者。
目标:深度学习在加速MRI方面表现出色,可通过欠采样k空间数据重建高质量图像。尽管近期工作利用多对比信息提升了重建性能,但这些方法依赖于监督学习,需全采样k空间作为训练参考。一种名为自监督数据欠采样(SSDU)的方法允许直接在欠采样k空间上训练,通过将k空间划分为两部分,由网络建立两者映射关系。本文提出两项改进以优化自监督MRI重建。方法:我们设计了一种多对比自监督学习框架,可在无全采样数据参考的情况下,联合训练多个欠采样对比图像。同时,以端到端方式学习每种对比的最优自监督数据划分策略,进一步提升重建质量。具体而言,我们学习一个最优划分概率分布,并据此采样生成掩码进行划分。结果:在两个公开的多对比MRI数据集上的实验表明,所提出的多对比自监督学习划分方法相较于当前单对比自监督方法,在重建质量上均有提升。我们还验证了学习k空间划分能进一步提高重建保真度。结论:结合多对比重建与学习划分的策略,显著优于单对比自监督重建。意义:该方法可在不依赖全采样k空间的前提下,实现更高图像保真度或更短扫描时间,推动自监督MRI技术发展。
原文摘要 · Abstract (English)
Objective: Deep Learning has shown promise in accelerating MRI by reconstructing high-quality images from under-sampled data. While recent work has leveraged multi-contrast information to improve reconstruction performance, these methods rely on supervised learning, which requires fully sampled k-space for training. One method, self-supervised learning via data undersampling (SSDU), enables direct training on under-sampled k-space by partitioning it into two sets, with a network mapping between the two. In this work, we improve MRI self-supervised MRI reconstruction with two modifications. Methods: We propose a multi-contrast self-supervised learning framework that jointly trains on multiple under-sampled contrasts without requiring fully sampled k-space data as a reference. Moreover, we learn an optimal self-supervised data partitioning for each contrast in an end-to-end manner, further enhancing reconstruction quality. Specifically, we learn an optimal partitioning probability distribution, which is sampled to generate a mask for partitioning. Results: Experiments on two publicly available multi-contrast MRI datasets demonstrate the improved reconstruction quality of our proposed self-supervised multi-contrast learned partitioning method compared to the current single-contrast self-supervised learning methods. We also demonstrate that learning the partitioning of k-space data further enhances the fidelity of reconstructions. Conclusion: Multi-contrast reconstruction combined with learned partitioning improves reconstruction fidelity over single-contrast self-supervised MRI reconstructions. Significance: Our method can facilitate higher image fidelity and/or accelerated MRI protocol times compared to previous self-supervised methods, and without requiring fully sampled k-space for training.
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