arXiv:2606.21329cs.LG2026-06中稿 · MICCAI 2026

针对医疗时间序列测试时自适应,实现无迭代快速泛化。

MedTS-TTT: Test-Time Training for Medical Time Series Classification

论文配图:MedTS-TTT: Test-Time Training for Medical Time Series Classification
图 1 · 摘自论文原文
  • 用单步快速权重更新实现测试时自适应,无需迭代优化。
  • 在4个公开数据集上12次评估中11次排名第一,优于9个基线。
  • 适合临床场景中个体差异大、需实时适配的医疗信号分类任务。

医疗时间序列(MedTS)信号如脑电图(EEG)和心电图(ECG)支持多种临床应用。然而,个体间显著异质性常导致个体级分布偏移,使固定参数模型难以泛化到未见个体。相比依赖额外适配模块或目标批次统计的领域自适应方法,测试时训练(TTT)通过利用无标签测试样本实现在线适配,更具实用性。但多数代表性TTT方法需迭代内环优化,增加测试时开销。本文提出MedTS-TTT,一种面向医疗时间序列建模的测试时训练框架。该框架基于闭环自对齐测试时训练(CLSA-TTT)与门控卷积主干网络(GCB)。CLSA-TTT构建令牌级自监督目标,进行单步快速权重更新以实现层内闭环对齐,实现无需迭代的快速样本级适配。GCB结合基于CLSA-TTT的快速适配与令牌级融合,引入门控卷积分支,平衡局部动态建模与信息流控制。在4个公共数据集(2个EEG、2个ECG)上采用个体独立划分的实验中,MedTS-TTT在12次评估(9个基线、3个指标)中取得11次第一名。代码已开源:https://github.com/mingzhi-c/MedTS-TTT。

原文摘要 · Abstract (English)

Medical time series (MedTS) signals such as electroencephalography (EEG) and electrocardiography (ECG) support many clinical applications. However, substantial subject-level heterogeneity often induces subject-level distribution shift, causing a fixed parameter set to generalize poorly to unseen individuals. Compared with domain adaptation methods that often depend on extra adaptation components or target-batch statistics, Test-Time Training (TTT) provides a more practical solution for sequential clinical data by enabling online adaptation from unlabeled test samples. However, many representative TTT methods require iterative inner-loop optimization, increasing test-time overhead. In this paper, we propose MedTS-TTT, a test-time training framework for medical time series modeling. MedTS-TTT is built upon Closed-Loop Self-Alignment Test-Time Training (CLSA-TTT) and a Gated Convolutional Backbone (GCB). CLSA-TTT constructs a token-level self-supervised target and performs a single-step fast-weight update for intra-layer closed-loop alignment, enabling rapid sample-wise adaptation without iterative inner-loop optimization. GCB combines CLSA-TTT-based fast adaptation and token-level fusion with a gated convolutional branch to balance local dynamic modeling and information-flow control. On 4 public datasets (2 EEG and 2 ECG) with subject-independent splits, MedTS-TTT achieves 11 top-1 rankings out of 12 evaluations across 9 baselines and 3 metrics. The code is publicly available at https://github.com/mingzhi-c/MedTS-TTT.

医疗时序测试时训练自适应

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