通过几何先验增强模型,精准分割肺血管细微结构。
MorVess: Morphology-Aware Pulmonary Vessel Segmentation Network

- 联合预测血管掩码、距离图和厚度图,显式约束形态连续性。
- 在两个肺CT数据集上,小血管恢复率与连通性显著提升。
- 适合需要高精度血管分析的医学影像研究者使用。
由于血管结构稀疏、迂曲且尺度多样,精确分割肺血管仍具挑战,小分支易丢失,拓扑完整性难以在体素级监督下保持。现有深度分割模型主要优化二值掩码,缺乏显式几何约束,难以恢复连续管状形态和精细连接。本文提出MorVess,一种融合可微几何先验与大规模基础模型适配的形态感知分割框架。该方法联合预测血管掩码、距离图和厚度图,为边界、中心线一致性及直径平滑过渡提供显式监督。轻量级2.5D适配器连接3D空间上下文与2D SAM表征,全局-局部融合模块聚合多层级语义与几何线索,实现高保真拓扑重建。在两个具有挑战性的肺CT基准上,MorVess在Dice、clDice和HD95指标上均优于现有方法,显著提升小血管恢复率与全局连通性。结果表明,将几何智能嵌入预训练视觉模型,为精准血管分析与临床可靠结构量化提供了系统化且可扩展的路径。代码已开源:https://github.com/MaoFuyou/MorVess。
原文摘要 · Abstract (English)
Accurate pulmonary vessel segmentation remains challenging due to the sparse, tortuous, and multi-scale nature of vascular structures, where small branches are easily lost and topology integrity is difficult to preserve under voxel-wise supervision. Existing deep segmentation models primarily optimize binary masks, lacking explicit geometric constraints, thus struggling to recover continuous tubular morphology and fine vascular connectivity. In this study, we introduce MorVess, a morphology-aware segmentation framework that integrates differentiable geometric priors with large-scale foundation model adaptation to achieve fine-grained vascular parsing. MorVess jointly predicts vessel masks, distance maps, and thickness maps, providing explicit supervision for vascular boundaries, centerline consistency, and smooth diameter transitions. A lightweight 2.5D adapter bridges 3D spatial context and 2D SAM representations, while a global-local fusion block aggregates multi-level semantics and geometric cues for high-fidelity topology reconstruction. Across two challenging pulmonary CT benchmarks, MorVess delivers superior Dice, clDice, and HD95 scores, substantially improving small-vessel recovery and global connectivity. These results demonstrate that embedding geometric intelligence into pretrained vision models offers a principled and scalable pathway toward precise vessel analysis and clinically reliable structural quantification. Our source code is available at https://github.com/MaoFuyou/MorVess.
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