arXiv:2606.27411quant-phcs.AI2026-06

用量子自编码器检测脑部MRI异常,通过压缩难易度判断病变。

Compression-Driven Anomaly Detection in Brain MRI Using an Interpretable Quantum Autoencoder

  • 将图像块转为量子态,通过可变编码器-解码器结构丢弃信息实现压缩驱动检测。
  • 切片级和像素级的ROC-AUC分别达0.95和0.813,优于经典方法。
  • 结果可解释,生成定位肿瘤的热力图,适合医疗影像辅助诊断。

本文研究用于脑部MRI异常检测的量子自编码器(QAE),通过角度编码将图像块映射为量子态,并采用变分编码器-解码器架构,利用辅助垃圾量子比特训练以丢弃信息。异常得分反映输入相对于正常数据的压缩抵抗程度,得分越高表示偏离学习到的正常流形越远。在公开的脑部MRI DICOM数据集上评估,该方法在切片级达到约0.95的ROC-AUC,像素级达约0.813,优于经典自编码器与PCA基线。参数分析显示编码器-解码器存在明显不对称性,有效异常检测源于编码器中结构化信息压缩,而非参数量或解码器表达能力提升。该方法实现可控的压缩-重建权衡,具备清晰的操作区间,支持合理阈值设定。定性评估表明,QAE生成的空间局部化异常热图与肿瘤区域高度一致。结果表明,量子自编码器基于对学习潜空间的不可压缩性,提供了一种可解释、可控制的异常检测机制,展现了其在量子机器学习中研究压缩动态的潜力,对医学影像决策支持具有重要意义。

原文摘要 · Abstract (English)

We study a quantum autoencoder (QAE) for compression-driven anomaly detection in brain MRI data. The approach leverages angle encoding to map image patches into quantum states, followed by a variational encoder-decoder architecture trained to discard information via auxiliary trash qubits. Anomaly scores reflect the degree to which inputs resist compression relative to normal data, with higher scores corresponding to deviations from the learned normal manifold. Evaluated on publicly available brain MRI DICOM datasets, the method achieves a slice-level ROC-AUC of approximately 0.95 and a patch-level ROC-AUC of approximately 0.813, outperforming classical autoencoder and PCA baselines. Analysis of the learned parameters reveals a pronounced encoder-decoder asymmetry, where effective anomaly detection arises from structured information compression within the encoder rather than increased parameter magnitude or decoder expressivity. This results in a controlled compression-reconstruction trade-off with a clear operating regime that supports principled threshold selection. Qualitative evaluation further shows that the QAE produces spatially localized anomaly heatmaps aligned with tumorous regions. The results, supported by promising baseline performances, demonstrate that quantum autoencoders provide an interpretable and controllable mechanism for anomaly detection based on incompressibility with respect to a learned latent representation. This work highlights the potential of quantum autoencoders as a principled tool for studying compression dynamics in quantum machine learning, with promising implications for decision support in medical imaging workflows.

量子机器学习异常检测医学影像自编码器

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