arXiv:2606.28453eess.IVcs.CV2026-06

用自回归建模提升低剂量CT去噪,保留更多解剖细节。

DeVAR: Low-Dose CT Denoising via Visual Autoregressive Modeling

论文配图:DeVAR: Low-Dose CT Denoising via Visual Autoregressive Modeling
图 1 · 摘自论文原文
  • 基于视觉自回归建模,逐步生成高保真正常剂量CT图像。
  • 在两个公开数据集上优于当前最佳方法,细节保留更佳。
  • 适合医学影像去噪研究者与临床医生关注图像质量提升。

计算机断层扫描(CT)在医学诊断中至关重要,但如何在降低辐射暴露的同时保持图像质量仍是关键挑战。低剂量CT(LDCT)虽可减少辐射风险,却伴随严重噪声和伪影,影响诊断准确性。现有深度学习方法虽有进展,但仍需更具全局到局部结构依赖建模能力的生成范式以更好保留精细解剖细节。为此,我们提出DeVAR,首次将视觉自回归建模(VAR)应用于LDCT去噪。该模型以LDCT前缀令牌提供的全局上下文为条件,通过逐尺度预测生成目标正常剂量CT(NDCT)的离散令牌图。由于量化会丢弃高频信息,我们引入残差精炼器以捕捉超出离散码本能力的微小解剖结构。最终,在双表示混合训练策略支持下,混合式NDCT解码器无缝融合连续与离散潜在表示,重建出高保真、细节丰富的图像。在两个公开数据集上的大量实验表明,DeVAR在定性与定量性能上均持续优于当前最优的LDCT去噪方法。

原文摘要 · Abstract (English)

Computed tomography (CT) plays a crucial role in medical diagnosis, but minimizing radiation exposure while maintaining image quality remains a critical challenge. Low-dose CT (LDCT) protocols reduce radiation risks but inevitably suffer from severe noise and artifacts that compromise diagnostic accuracy. While existing deep learning methods have achieved promising results, there remains a continuous quest for generative paradigms that intrinsically capture global-to-local structural dependencies to better preserve fine anatomical details. To this end, we propose DeVAR, a novel generative framework that applies visual autoregressive modeling (VAR) to LDCT denoising for the first time. Conditioned on global context provided by LDCT prefix tokens, DeVAR progressively generates discrete token maps of the target normal-dose CT (NDCT) via next-scale prediction. Because quantization inherently discards high-frequency information, we introduce a residual refiner to capture subtle anatomical structures beyond the capacity of a discrete codebook. Finally, empowered by a dual-representation hybrid training strategy, our hybrid NDCT decoder seamlessly integrates continuous and discrete latents to reconstruct high-fidelity, detail-preserved images. Extensive experiments on two public datasets demonstrate that DeVAR consistently achieves superior qualitative and quantitative performance compared to state-of-the-art LDCT denoising methods.

CT去噪自回归模型生成模型

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