提出首个超高清多焦点图像融合数据集与轻量级查询表框架，实现4K实时融合。

With the advancement of imaging technology, ultra-high-definition images have become increasingly essential in modern visual applications. However, existing multi-focus image fusion remains largely confined to low-resolution images and faces three major barriers in UHD scenarios, namely data availability, model adaptability, and deployment feasibility, which severely hinder its practical application. To shatter these barriers, first, we propose the UHD-MFF dataset, the first large-scale ultra-high-resolution multi-focus fusion dataset. Second, we propose a scale-specialized lookup-table framework tailored for ultra-high-resolution images, termed as UMF-LUT. It consists of Coarse-Region Lookup Table (C-LUT) and Detail-Edge Lookup Table (D-LUT). Specifically, C-LUT performs joint queries of multiple gradient cues and semantic cues at low-resolution scales to enable region-level decision-making. Also, D-LUT operates at high-resolution scales, leveraging efficient Laplacian cues to provide complementary edge-level decision information. Such a design makes the model particularly well-suited for ultra-high-resolution multi-focus image fusion. Finally, it offers strong deployability with minimal computational overhead, enabling real-time 4K multi-focus fusion and showing promising potential for smartphone. Extensive experiments demonstrate that it outperforms SOTA methods in both visual fidelity and quantitative metrics. It effectively advances the development of multi-focus image fusion toward ultra-high-resolution imaging scenarios. The code is available at https://github.com/zyb5/UHD-MFF.