仅用少量参考图即可完成产前超声异常分类与定位,无需训练。
Prototype Memory-Guided Training-Free Anomaly Classification and Localization in Prenatal Ultrasound

- 构建多粒度原型记忆库,捕捉异常特征与类别语义。
- 在9类异常上实现优于竞品的检测准确率,跨中心数据表现稳定。
- 适合资源有限的临床场景,无需微调即可部署使用。
产前异常分类与定位对胎儿健康和妊娠管理至关重要。尽管超声是主要筛查手段,但异常发生率低且形态多样,导致诊断困难。现有深度学习方法依赖大规模标注数据,难以获取;少样本学习虽缓解数据稀缺,但通常需针对新类别微调,不适用于资源有限的临床环境。为此,我们提出首个无需训练的多类别产前超声异常分类与定位框架,仅需每类少量参考图像。框架包含三部分:(1) 多粒度原型记忆库,显式建模类别语义与异常特征;(2) 原型驱动的软融合机制,聚合判别性特征以定位异常区域;(3) 类别感知精炼策略,利用原型一致性提升分类精度。在包含1,149例、共2,357张图像、9个类别的多中心数据集上验证,性能优于现有方法。
原文摘要 · Abstract (English)
Prenatal anomaly classification and localization is of critical importance for fetal health and pregnancy management. Although ultrasound (US) is the primary modality for prenatal screening, accurate diagnosis remains challenging due to the low prevalence and high heterogeneity of anomalies. Existing deep learning methods for prenatal tasks rely on large-scale annotated datasets, which are difficult to obtain in practice. Although few-shot learning alleviates data scarcity, it typically requires fine-tuning for new categories, limiting its practicality in resource-limited clinical settings. To address these challenges, we propose a training-free framework for multi-class prenatal US anomaly classification and localization that operates with only a few reference images per class, representing the first exploration of this setting. Our framework comprises three key components: (1) a memory bank with multi-granular prototypes that explicitly models both class-level semantics and anomaly characteristics; (2) a prototype-driven soft merging mechanism that aggregates discriminative features to detect the anomaly region; and (3) a class-aware refinement strategy that leverages prototype consistency to improve category prediction. Extensively validated on a multi-center prenatal US dataset containing 1,149 cases, with a total of 2,357 images and 9 categories, our proposed method outperforms the competitors.
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