arXiv:2607.02156cs.CV2026-07

仅用一次全身CT扫描,构建可动的个性化人体数字孪生模型。

Patient-Specific Articulated Digital Twins from a Single Full-Body CT Scan

论文配图:Patient-Specific Articulated Digital Twins from a Single Full-Body CT Scan
图 1 · 摘自论文原文
  • 基于SMPL模型拟合患者骨架,建立可调节姿态的骨骼框架。
  • 在未见姿态下保持94.4%以上的骨骼包裹率,重建图像相似度达0.872。
  • 适用于手术规划、影像模拟等需动态体位变化的医学场景。

个体化解剖模型为手术规划、影像引导干预和算法开发提供精准参照。然而,多数基于CT构建的模型为静态:仅保留扫描时的身体姿态,无法模拟患者重新摆放后的形态变化,这对依赖成像几何与体位的放射成像尤为关键。本文提出一种从单次全身CT扫描构建患者特异性可动数字孪生的可行性验证方法。该方法通过将参数化人体模型(SMPL)拟合至患者数据,获得对齐的运动学骨架,将分割出的骨骼与器官绑定至感知解剖结构的驱动系统,并在保持骨骼几何的前提下重定向体位变化。在三名全身影像受试者上,拟合骨架的切比雪夫距离为15.8 ± 4.0 mm,骨骼包裹率达95.9 ± 1.8%。在原始采集体位下重构的图像保持主要放射结构,配对的数字化射线照片(DRR)整体结构相似性(SSIM)为0.872 ± 0.016,峰值信噪比(PSNR)达18.5 ± 1.4 dB。在未见过的目标体位上,数字孪生仍能实现灵活关节运动,同时维持94.4 ± 0.4%的高骨骼包裹率。作为可行性演示,我们生成了随体位变化的数字射线照片。结果表明,静态、视角可控的CT仿真有望拓展为姿态可控的解剖数字孪生,服务于未来合成影像与体位研究。

原文摘要 · Abstract (English)

Patient-specific anatomical models provide individualized context for surgical planning, image-guided intervention, and algorithm development. However, most CT-derived models are static: they preserve the body configuration captured at scan time, but cannot represent how the same anatomy would appear after patient repositioning. This limitation is especially important for radiographic imaging, where appearance depends jointly on imaging geometry and patient pose. We present a proof-of-concept for constructing a patient-specific articulated digital twin from a single full-body CT scan. The method fits a parametric human body model (SMPL) to obtain a patient-aligned kinematic scaffold, binds segmented bones and organs to an anatomy-aware rig, and retargets body-pose changes while preserving skeletal geometry. On three full-body CT subjects, the fitted scaffold achieved 15.8 $\pm$ 4.0 mm chamfer distance and 95.9 $\pm$ 1.8% skeletal enclosure. Recomposition at the acquisition pose preserved major radiographic structure, with overall SSIM of 0.872 $\pm$ 0.016 and PSNR of 18.5 $\pm$ 1.4 dB across paired DRRs. Across unseen target poses, the resulting twins enabled articulation while maintaining high skeletal enclosure (94.4 $\pm$ 0.4%). As a feasibility demonstration, we render the articulated twin as pose-dependent DRRs. These results suggest the feasibility of extending static, view-controllable CT simulation toward pose-controllable anatomical twins for future synthetic imaging and positioning studies.

数字孪生医学影像体位重建3D建模

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