arXiv:2607.02670cs.LG2026-07

提出多尺度脑电特征框架,提升精神障碍维度预测能力。

A Granularity-Aware EEG Feature Framework for Psychopathology Dimension Prediction

论文配图:A Granularity-Aware EEG Feature Framework for Psychopathology Dimension Prediction
图 1 · 摘自论文原文
  • 按全局、区域、通道层级组织脑电特征,实现粒度感知
  • 在四类心理问题预测中,模型表现优于传统方法但效果有限
  • 揭示特定维度的脑区与频段模式,适合未来脑电表型研究

脑电图(EEG)为研究维度化精神障碍的神经生理基础提供了无创手段,但跨范式与特征粒度的系统性证据仍有限。本文构建了一种粒度感知的脑电特征流程,将多尺度描述符分为全局、区域和通道三个层级。基于健康大脑网络(HBN)队列,评估了四种精神障碍维度(p因子、内化问题、外化问题、注意力问题)在四种脑电范式下的预测效果。鉴于儿童精神障碍的异质性及问卷评分的中等信度,该设置更侧重可行性验证而非临床筛查。树模型结合粒度平衡特征选择,在部分条件下表现优于传统方法,但效应量仍较小。所选标志物的可视化显示其空间与频谱模式与现有神经生理知识基本一致。对独立的PEARL队列进行探索性跨数据集检验表明,该选择原则在协议变化下仍具技术可行性,但不保证泛化性能。总体而言,多尺度脑电特征包含微弱但可检测的精神障碍相关信号,粒度感知筛选可作为未来脑电表型研究的有效降维策略。

原文摘要 · Abstract (English)

Electroencephalography (EEG) offers a noninvasive approach for examining neurophysiological correlates of dimensional psychopathology, yet systematic evidence across EEG paradigms and feature granularities remains limited. Here, we develop a granularity-aware EEG feature pipeline that organizes multi-scale descriptors into global, regional, and channel levels. Using the Healthy Brain Network (HBN) cohort, we evaluate the prediction of four psychopathology dimensions: p-factor, internalizing, externalizing, and attention problems, across four EEG paradigms. Given the heterogeneity of pediatric psychopathology and the moderate reliability of questionnaire-derived scores, this setting represents a challenging feasibility test rather than a clinical screening scenario. Tree-based models and granularity-balanced feature selection showed promising improvements over conventional approaches in selected conditions, although effect sizes remained modest. Visualization of selected markers revealed dimension-specific spatial and spectral patterns that were broadly aligned with existing neurophysiological knowledge. An exploratory cross-dataset sanity check on the independent PEARL cohort suggested that the proposed selection principle remains technically feasible under protocol shifts, without claiming cross-dataset generalizability. Overall, multi-scale EEG features contain weak but detectable signals related to dimensional psychopathology, and granularity-aware selection may serve as a useful feature-reduction strategy for future EEG-based phenotyping studies.

脑电分析精神障碍多尺度特征表型研究

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