arXiv:2607.04025cs.IRcs.HC2026-07

动态构建双超图,让中医处方可审计可解释。

Patient-Conditioned Dual Hypergraph Reasoning for Auditable Traditional Chinese Medicine Prescription Support

论文配图:Patient-Conditioned Dual Hypergraph Reasoning for Auditable Traditional Chinese Medicine Prescription Support
图 1 · 摘自论文原文
  • 用双超图建模症状与用药逻辑,按患者情况动态加权路径。
  • 在真实数据集上实现0.8297的证候识别准确率,草药推荐F1达0.3111。
  • 适合需要可解释性的中医辅助诊疗系统,尤其关注处方可审计性。

中医处方支持需从临床描述中推理出证候、治则、药物及剂量,但直接生成模型决策难以追溯依据。静态知识库虽提供先验信息,却无法针对个体患者确定关键诊断与处方关系。本文提出患者条件化的双超图框架:第一超图围绕证候与治则推理整合症状、舌脉等临床证据;第二超图则聚焦证候、疾病背景、药物、剂量先验等构建处方生成逻辑。两个超图均根据患者表征动态调整权重,实现个性化诊断路径激活与用药推荐,并保持病例级可审计性。在TCM-SD数据集上,第一超图使MacBERT证候识别准确率达0.8297,宏F1为0.3288;在TCM-BEST4SDT上,第二超图获得0.3111的平均草药F1,全链路管道达0.3074,接近理想设定。50例真实病例的临床审计验证了实用性,但仍需前瞻性剂量安全性验证。

原文摘要 · Abstract (English)

Traditional Chinese medicine (TCM) prescription support requires patient-specific reasoning from clinical narratives to syndromes, treatment principles, herbs, and doses. Direct language-model generation can produce fluent prescriptions, but its decisions are difficult to audit against explicit clinical evidence. Static TCM knowledge resources provide useful priors, but they cannot determine which diagnostic and prescription relations should be emphasized for an individual patient. We propose a patient-conditioned dual hypergraph framework for auditable TCM prescription support. The first hypergraph organizes symptom, tongue, pulse, and other clinical evidence around syndrome and treatment-principle reasoning. The second hypergraph organizes syndrome, treatment, disease-context, herb, retrieval, and dose-prior evidence for prescription construction. Unlike static knowledge graphs or fixed hypergraphs, both hypergraphs are dynamically weighted by the patient representation. This design enables individualized activation of diagnostic and prescription paths, supporting personalized syndrome differentiation and herb-dose recommendation while preserving case-level auditability. Experiments on TCM-SD show that dynamic weighting in the first hypergraph improves MacBERT syndrome differentiation to 0.8297 accuracy and 0.3288 macro-F1. On TCM-BEST4SDT, the second hypergraph achieves the best mean Herb-F1 of 0.3111 across three seeds, and the full connected pipeline reaches 0.3074 Herb-F1, close to the oracle setting. A 50-case real-world CAP audit further suggests practical review potential, while highlighting the need for prospective dose-safety validation.

中医AI可解释性超图建模处方生成

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