用深度学习自动识别计数白细胞,准确率超99%。
LeukocyteCount: Automatic Identification and Counting for leukocytes using Deep Learning

- 用YOLOv5检测白细胞,再用MobileNetV2+逻辑回归分类
- 白细胞分类准确率达99.04%,红细胞检测F1值99.73%
- 适合医学影像分析、自动化检验系统开发者参考
疾病诊断与监测常依赖人体生物样本分析,其中血细胞分析尤为关键。白细胞(WBC)是评估机体免疫防御的重要指标。传统人工计数方法耗时且易出错。本文提出一种基于深度学习的自动化解决方案:结合YOLOv5检测白细胞,再通过预训练的MobileNetV2与逻辑回归分类器实现四种类型精准分类。模型在BCCD数据集上训练验证,检测准确率达98%,分类准确率高达99.04%;同时基于YOLOv5的红细胞检测模块取得99.73%的F1分数,优于基线。结果表明该模型可显著提升白细胞分析的准确性与效率,推动实验室检测向智能化发展。
原文摘要 · Abstract (English)
Diagnosing and monitoring diseases frequently involves the analysis of human biological samples, with blood analysis being pivotal. Specifically, leukocytes, or white blood cells (WBCs), are essential markers for evaluating the body's defense mechanisms against infections. Traditional methods for WBC counting and classification are labor-intensive and prone to inaccuracies, primarily due to human error. The conventional processes for blood cell analysis, especially those concerning WBCs, are beset with difficulties. These include the laborious nature of manual counting and the susceptibility to errors, which can significantly impact the accuracy and reliability of disease diagnosis and monitoring. This study proposes an automated, machine learning-based solution aimed at mitigating the identified challenges. By employing a hybrid model that integrates Yolov5 for the detection of WBCs, coupled with a finely tuned, pre-trained MobileNetV2 model and a Logistic Regression classifier, the study innovates in the accurate identification, counting, and classification of WBCs into four distinct types. The methodology leverages the BCCD dataset for training and validation purposes. The application of the proposed hybrid machine learning model has yielded remarkable results, demonstrating a detection accuracy rate of 98\% through the Yolov5 stage, and an unparalleled classification accuracy of 99.04\% in subsequent stages utilizing MobileNetV2 and Logistic Regression. Additionally, Our proposed YOLOv5-based RBC detection module achieves an F1 score of 99.73\%, which outperforms the baseline. These findings underscore the model's potential in transforming traditional laboratory practices for WBC analysis, offering a path towards more accurate, efficient, and reliable disease diagnostics and monitoring.
Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。