通过几何对齐提升冠状动脉造影多视角报告准确性
MAC-XA: Multi-view Anatomy-Correspondence Fusion for Coronary Stenosis Reporting from X-ray Angiography

- 构建显式解剖对应模块,实现多视角图像的精准空间对齐
- 在合成数据上提升对应一致性,零样本迁移至真实数据表现更优
- 适合医学影像分析、智能诊断系统研发人员参考
冠状动脉造影的多视角推理本质上是跨投影几何问题。三维血管拓扑导致分支重叠和缩短,单视角建模难以稳定定位病变和评估狭窄程度。尽管多视角融合有潜力,但真实造影中视角间对齐不可观测,无法显式监督,传统方法依赖隐式相关性而非真实解剖对应。本文将多视角狭窄报告重构为约束对齐的聚合问题,提出可控合成造影生成策略,暴露几何推导的像素级对应监督。引入解剖对应模块,在主视角坐标系中显式对齐辅助特征,约束证据聚合于解剖一致区域。在合成数据上的实验及零样本迁移到真实数据均表明,该方法显著提升对应一致性与结构化报告质量,优于单视角和传统多视角融合方法。代码将在发表后公开。
原文摘要 · Abstract (English)
Multi-view reasoning in coronary X-ray angiography is inherently a cross-projection geometric problem, yet automated report generation in this setting remains largely unexplored. The 3D vascular topology leads to projection-dependent branch overlap and foreshortening, rendering single-view modeling fundamentally incomplete and unstable for lesion localization and stenosis grading. Although multi-view fusion appears promising, learning anatomically consistent fusion from real angiograms is impeded by a critical limitation: cross-view alignment is unobservable and cannot be explicitly supervised. Consequently, conventional fusion relies on implicit correlations rather than verified anatomical correspondence. We address this by reformulating multi-view stenosis reporting as an alignment-constrained aggregation problem. A controllable synthetic angiography generation strategy is introduced to expose geometry-derived patch-level correspondence supervision unavailable in real data. An anatomy-correspondence module learns cross-view correspondence matrices that explicitly align auxiliary features within the main-view coordinate space prior to fusion, thereby constraining evidence aggregation to anatomically consistent regions. Experiments on synthetic data and zero-shot transfer to real angiograms show that this alignment-constrained design improves correspondence consistency and structured stenosis reporting compared to single-view modeling and conventional multi-view fusion methods. The code will be publicly available upon publication.
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