LLM让假信息从内容造假升级为系统性威胁，本文构建框架统一分析攻防漏洞。

Large language models (LLMs) have transformed misinformation from a primarily content-centric problem into a broader ecosystem-level security challenge. When misused, LLMs create risks beyond false content generation, enabling attacks on the social contexts, evidence sources, retrieval corpora, and verification workflows that misinformation defense depends on. In this paper, we introduce a role-layer framework to unify these risks and defenses. The role dimension characterizes LLMs as attackers, defenders, and vulnerable components of verification systems, while the layer dimension covers content, social contexts, evidence environments, and verification workflows. Guided by this framework, we organize LLM-enabled attacks, investigate LLM-based detection and verification methods, analyze vulnerabilities in LLM-centric detection paradigms, and discuss existing countermeasures against LLM-enabled attacks. Building on this synthesis, we identify three key open challenges: moving from static detection accuracy to budgeted ecosystem-level risk evaluation, hardening LLM-centered verification pipelines against adversarial manipulation, and deploying auditable human-in-the-loop verification systems for trustworthy real-world misinformation defense.