arXiv:2607.14195eess.IV2026-07

提出一套量化颈内动脉弯曲度的混合框架,提升脑血管评估客观性。

A Hybrid Framework for Blood Vessel Morphology Classification: Discrete Geometry-based Tortuosity Feature Measurement, Information Gain-based Feature Selection, and Random Forest Classification

论文配图:A Hybrid Framework for Blood Vessel Morphology Classification: Discrete Geometry-based Tortuosity Feature Measurement, Information Gain-based Feature Selection, and Random Forest Classification
图 1 · 摘自论文原文
  • 基于离散几何测量血管弯曲特征,结合信息增益筛选关键指标。
  • 二分类准确率达92.06%,三分类达86.26%,效果优于传统方法。
  • 构建形态风险指数MRI,可为临床提供直观数值参考。

血管弯曲度的主观评价依赖临床经验,传统距离指标难以刻画三维空间变形。因异常颈内动脉(ICA-C1)形态与脑血管评估及卒中风险相关,客观可重复的弯曲度量化至关重要。本文提出一种融合离散几何特征测量、基于信息增益的特征选择与随机森林分类的混合框架。从379例临床血管中心线提取13个弯曲度特征,经筛选保留$ ext{TI}$、$ ext{AC}$、$ ext{TC}$、$ ext{AC}/ ext{AT}$、$ ext{AT}$、$ ext{TT}$共六个特征。在二分类(非严重与严重弯曲)任务中,随机森林模型宏平均F1达0.9206;在三分类(直、低弯曲、高弯曲)任务中,宏平均F1达0.8626。结果表明,伸长与曲率特征对初步筛查有强判别力,扭转变形特征则有助于精细化分类。基于随机森林特征重要性,进一步定义形态风险指数(MRI),为血管形态提供直接数值参考,有望实现更客观一致的临床评估。

原文摘要 · Abstract (English)

Subjective visual grading of blood vessel tortuosity relies heavily on clinical experience, while traditional distance-based indices often fail to adequately characterize three-dimensional spatial deformation. Because abnormal internal carotid artery morphology may be clinically relevant to cerebrovascular assessment and stroke-risk evaluation, objective and reproducible quantification of vascular tortuosity is of considerable importance. To address this limitation, we propose a mathematical framework for the morphological classification of the internal carotid artery (ICA-C1) segment. The framework integrates discrete geometric feature measurement, Information Gain-based feature selection, and Random Forest classification. An initial set of 13 tortuosity features is extracted from the corresponding 379 clinical vascular centerlines using discrete geometric methods and subsequently reduced to a six-feature subset consisting of $\mathcal{TI}$, $\mathcal{AC}$, $\mathcal{TC}$, $\mathcal{AC}/\mathcal{AT}$, $\mathcal{AT}$, and $\mathcal{TT}$. The framework is evaluated in two classification tasks. For binary classification of non-severe and severe tortuosity, the RF model achieves a Macro-F1 score of 0.9206. For ternary morphological grading into straight, low-tortuosity, and high-tortuosity groups, it achieves a Macro-F1 score of 0.8626. The results indicate that elongation- and curvature-related features provide strong discriminatory information for basic screening, whereas torsion-related features contribute additional information for more detailed morphological classification. Based on the RF feature-importance values, we further define a Morphological Risk Index (MRI), which provides a direct numerical reference for vascular morphology and may facilitate more objective and consistent clinical assessment.

血管分析形态分类随机森林风险指数

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