用语义通信优化车路协同，减少冗余信号，提升路口通行效率。

Vehicle coordination at unsignalized intersections relies on accurate real-time vehicle state acquisition and reliable command-and-control (C&C) signal delivery. However, existing studies typically treat sensing, communication, and control separately, which may lead to redundant transmissions, outdated state information, and unreliable vehicle coordination. In this paper, we investigate a new scenario of distributed integrated sensing and communication (ISAC)-enabled vehicle coordination at intersections, where multiple roadside units (RSUs) collaboratively transmit sensing signals for vehicle state acquisition and C&C signals for vehicle movement control under the management of a central base station (BS). To improve signaling efficiency, we propose a unified goal-oriented semantic communication (GSC) framework, which transmits sensing and C&C signals only when they are semantically important for improving intersection traffic throughput. Specifically, an extended Kalman filter (EKF) is adopted to predict vehicle states and fuse distributed sensing measurements. A masked hybrid proximal policy optimization (MHPPO) framework is then developed to jointly determine sensing transmission decisions, C&C transmission decisions, and C&C signal contents based on a value-of-information (VoI) reward. Furthermore, we propose an uncertainty-aware transmission design (UTD), including robust beamforming and VoI-based time-division power allocation, to improve sensing and communication reliability under vehicle state uncertainty and inter-RSU interference. Simulation results show that our proposed framework achieves 100% collision-free vehicle coordination with significantly reduced signaling overhead compared with predictive ISAC baselines adapted from state-of-the-art related studies and several ablation baselines.