arXiv:2607.19006cs.LGq-bio.QM2026-07中稿 · the IEEE EMBC 2026…

基于个体特征的血糖预测模型,提升糖尿病管理精准度

Subject-Conditioned Glucose Forecasting in Type-1 Diabetes

论文配图:Subject-Conditioned Glucose Forecasting in Type-1 Diabetes
图 1 · 摘自论文原文
  • 用个体特异性表征显式建模,分离人群差异与血糖动态
  • 在两个基准数据集上均实现更优预测效果,多时序下事件预警更可靠
  • 适合个性化糖尿病管理研究者与临床辅助系统开发者

准确预测血糖浓度对1型糖尿病管理至关重要,有助于早期发现异常血糖事件并支持及时治疗干预。尽管近年血糖预测取得进展,现有方法多依赖群体层面表示或隐式个性化策略,难以提供有效的个体化预测。本文提出一种新型多模态深度学习架构——主体条件血糖预测(SCGP),通过结合观测血糖数据和从上下文信息中学习到的紧凑个体表征,显式地进行主体特征建模与血糖动态分离,避免异构输入过早融合,有效捕捉个体间差异的同时保持可靠的时序建模能力。在两个主流基准数据集上的实验表明,SCGP持续提升预测性能,在多个预测时长下均能实现对不良血糖事件的可靠检测,凸显显式主体条件化在个性化糖尿病管理中的优势。

原文摘要 · Abstract (English)

Accurate forecasting of blood glucose concentration is key in the management of Type 1 Diabetes, facilitating early detection of adverse glycemic events and supporting timely therapeutic interventions. Despite recent advances in glucose prediction, most existing approaches rely on population-level representations or implicit personalization strategies that fail to deliver effective subject-specific forecasts. In this work, we propose Subject-Conditioned Glucose Prediction (SCGP), a novel multimodal deep learning architecture conceived for personalized blood glucose prediction. SCGP conditions glucose predictions based on observed glucose data and a compact subject-specific representation learned from contextual information. By explicitly separating subject characterization from glucose dynamics modeling and avoiding early fusion of heterogeneous inputs, the proposed framework effectively captures inter-subject variability while preserving robust and reliable temporal modeling. Experiments on two state-of-the-art benchmark datasets demonstrate that SCGP consistently improves forecasting performance, enabling reliable detection of adverse glycemic events across multiple prediction horizons, highlighting the benefits of explicit subject conditioning for personalized diabetes management.

血糖预测个性化医疗深度学习1型糖尿病

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