arXiv:2607.19274cs.RO2026-07

新型自膨胀机器人可安全进入脊髓蛛网膜下腔,实现精准导航与成像。

Eversion-based robots can enable safe access,steering and endoscopic imaging within the spinal subarachnoid space

论文配图:Eversion-based robots can enable safe access,steering and endoscopic imaging within the spinal subarachnoid space
图 1 · 摘自论文原文
  • 通过末端外翻生长方式推进,减少摩擦与组织剪切力。
  • 在尸体实验中实现150毫米可控延伸,交互力降低超48%。
  • 集成微型内窥镜,适合脊髓内介入手术与微创诊疗研究者。

脊髓蛛网膜下腔空间狭窄、柔软且脆弱,传统导管与连续体机器人依赖近端推入,易产生界面摩擦与剪切力,限制远端控制并增加神经损伤风险。本文提出一种直径2毫米的自外翻生长机器人平台,可在人体蛛网膜下腔实现低摩擦延伸与精准转向。通过计算建模、假体实验及完整人体尸解验证:假体实验显示平均交互力降低65.2%,峰值交互力降低48.0%;物理模型表明外翻推进可重构组织受力分布,降低局部应力集中与界面剪切。在完整人体尸解中,系统从标准腰椎穿刺点实现150毫米可控内鞘延伸,同步完成荧光透视与内窥镜可视化,覆盖多个椎体节段。术后椎板切除与硬膜切开检查未发现硬膜或周围神经结构的明显宏观损伤。该研究首次在完整人体解剖中实现外翻式机器人的力学表征与多模态验证,为未来脊髓内介入治疗奠定定量与操作基础。后续需在更大样本与生理条件下验证其临床转化可行性。

原文摘要 · Abstract (English)

Safe navigation within the spinal subarachnoid space is constrained by its narrow, compliant, and delicate anatomy. Conventional catheters and continuum robots rely on proximal pushing, generating friction and shear along the tissue device interface that limit distal controllability and increase the risk of neural injury. Here, we present a 2 mm diameter eversion-growing robotic platform that enables friction minimised extension and steering within the human spinal subarachnoid space, validated through computational modelling, phantom experiments, and intact human cadaver studies. The robot integrates a miniature endoscope for real time intrathecal visualisation and advances by pressure driven tip eversion, localising motion to the distal tip while minimising translational sliding of the deployed body. Phantom experiments demonstrated reductions of 65.2% in mean interaction force and 48.0% in peak interaction force compared with matched push-based insertion. Physics based modelling showed that eversion based growth redistributed tissue loading, reducing local stress concentrations and interfacial shear relative to conventional insertion. In an intact human cadaver, the system achieved 150 mm of controlled intrathecal extension with concurrent fluoroscopic and endoscopic visualisation, providing access across multiple vertebral levels from a standard lumbar entry point. Postprocedural laminectomy and durotomy revealed no observable macroscopic disruption of the dura mater or surrounding neural structures. These results provide the first mechanically characterised and multimodally validated demonstration of eversion-based robotic navigation in intact human spinal anatomy, establishing a quantitative and procedural foundation for future intrathecal interventions. Further validation in larger anatomical cohorts and under physiological conditions will be required before clinical translation.

机器人手术脊髓介入内窥镜柔性机器人

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