arXiv:2607.19532cs.LGcs.AI2026-07

用联邦学习保护隐私,实现乳腺癌进展预测的跨机构协作建模。

Trustworthy Privacy-Preserving Multimodal Federated Learning for Personalised Breast Cancer Prediction

论文配图:Trustworthy Privacy-Preserving Multimodal Federated Learning for Personalised Breast Cancer Prediction
图 1 · 摘自论文原文
  • 基于多模态数据的联邦学习框架,融合影像与临床信息。
  • 性能接近中心化模型,且保持数据本地化不外泄。
  • 兼顾透明性、公平性,适合医疗多中心协作场景。

联邦学习为敏感健康数据建模提供了隐私保护方案,尤其适用于个性化癌症诊疗。本研究探索联邦学习在乳腺癌肿瘤进展预测中的应用,评估其在透明性、可扩展性、安全性和公平性四方面的能力。采用包括临床信息、肿瘤特征、生物标志物及患者人口统计学数据,结合MRI影像等多模态数据,构建随时间变化的肿瘤特征模型。对比了联邦学习与集中式训练模型的性能,并进一步研究了安全更新策略、跨患者亚组性能保持及机构间可扩展性。结果表明,联邦学习可在不共享原始数据的前提下,达到接近集中式模型的预测效果,验证了隐私保护下多模态建模的可行性,为数字孪生等个性化治疗规划提供支持。

原文摘要 · Abstract (English)

Federated learning has emerged as a potential solution to privacy concerns associated with using sensitive health data for training predictive models, particularly in personalised cancer care. This research investigates whether federated learning can support the development of robust models for predicting tumour progression in breast cancer patients while addressing four critical deployment pillars: transparency, scalability, security, and fairness. This study evaluates a federated learning framework using multimodal data, including clinical information, tumour characteristics, biomarker data, and patient demographics, alongside medical imaging data such as MRI scans, to model changes in tumour characteristics over time. The performance of the federated approach was compared with that of a centralised model trained on aggregated data. The report then further examines strategies to enhance secure model updates, maintain performance across patient subgroups, and support scalability across institutions. The findings assess whether federated learning can achieve predictive performance comparable to centralised learning while preserving data locality. These results contribute to understanding the feasibility of privacy-preserving, multimodal predictive modelling and support future applications such as digital twins to assist clinicians and patients in personalised treatment planning.

联邦学习乳腺癌多模态隐私保护

Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。