arXiv:2607.21859cs.AI2026-07

用文献证据自动生成可审计的因果图,提升生物医学研究可信度。

EviDAG: Auditable Causal DAG Authoring with Biomedical Literature

论文配图:EviDAG: Auditable Causal DAG Authoring with Biomedical Literature
图 1 · 摘自论文原文
  • 基于文本描述自动提取文献证据,生成结构化因果判断
  • 在基准数据集上实现高边召回率,且每条边均有可追溯证据
  • 适合需要可验证因果假设的研究者与审稿人使用

构建因果有向无环图(DAG)是生物医学因果分析的核心步骤,但目前仍高度依赖人工。研究人员需将变量关联到已有文献,评估不确定的因果主张,并保留足够溯源信息以供专家审查。我们提出EviDAG,一个基于浏览器的系统,支持从生物医学文献中构建可审计、证据链接的因果DAG。给定研究概念的自由文本描述,EviDAG生成可复现的文献快照,利用大模型推理模块生成成对因果判断,将支持性判断与原文摘录关联,并组装为经约束检查的图结构。每个提议边均包含置信度估计、溯源信息和可审查理由。界面支持研究设定、进度监控、证据审查、图比较、调整集计算及导出。在紧凑基准DAG与基于发表文献构建的参考DAG上的评估显示,EviDAG在文献驱动队列中达到高边召回率,且相比仅依赖LLM的基线,具备可验证的证据链。因此,EviDAG降低了因果图维护负担,同时使假设可审计,助力生物医学研究的设计、分析与解释。

原文摘要 · Abstract (English)

Constructing causal directed acyclic graphs (DAGs) is a core step in biomedical causal analysis, yet it remains a largely manual process. Analysts must connect study variables to prior literature, evaluate uncertain causal claims, and preserve sufficient provenance for expert review. We present EviDAG, a browser-based system for authoring causal DAGs as auditable, evidence-linked artifacts from biomedical literature. Given free-text descriptions of study concepts, EviDAG creates a reproducible literature snapshot, uses an LLM-based reasoning module to generate structured pairwise causal judgments, links literature-supported judgments to verbatim evidence excerpts, and assembles the judgments into a constraint-checked graph. Each proposed edge includes confidence estimates, provenance, and a reviewable rationale. The interface supports study specification, progress monitoring, evidence review, graph comparison, adjustment-set computation, and export. In evaluations against both compact benchmark DAGs and reference DAGs derived from published literature, EviDAG achieves high edge recall on the literature-based cohort while retaining verifiable evidence trails absent from LLM-only baselines. EviDAG thus reduces the burden of causal DAG curation while making the resulting assumptions auditable, supporting the design, analysis, and interpretation of biomedical studies.

因果推断文献挖掘可审计性DAG生成

Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。