扩散模型让医学影像修复更逼真,这篇综述梳理了方法、挑战与未来方向。
Diffusion Models in Medical Image Inpainting: Challenges, Solution Taxonomy, and Future Directions

- 提出扩散模型在医学图像修复中的分类体系
- 60项研究显示其在磁共振与CT中显著提升修复质量
- 适合临床科研人员关注技术瓶颈与数据标准
图像修复旨在重建图像中缺失或受损区域,同时尽可能保持视觉和语义一致性。在医学影像中,伪影、信息缺失及病灶改变可能影响诊断可靠性与下游临床应用。近年来,扩散模型因其生成解剖结构一致结果的能力,成为医学图像修复的前沿方法。本综述系统分析了60项基于扩散模型的医学图像修复研究,涵盖主流架构、应用场景、数据集与评估策略。我们提出了扩散模型方法的分类体系。分析表明该领域研究快速增长,去噪扩散概率模型与潜在扩散模型成为主流架构。研究主要聚焦于伪影去除、数据增强、伪健康组织重建与异常检测,尤其在磁共振成像(MRI)与计算机断层扫描(CT)中表现突出。总体而言,扩散模型在生成解剖合理重建方面表现优异,并有助于下游临床任务。但研究仍面临缺乏标准化基准、数据集多样性不足、跨临床场景验证受限等挑战。
原文摘要 · Abstract (English)
Image inpainting aims to reconstruct missing or corrupted regions of an image while preserving as much as possible, visual and semantic consistency. In medical imaging, this task is particularly important because artifacts, missing information, and pathological alterations can compromise diagnostic reliability and downstream clinical applications. Recently, diffusion models have emerged as state-of-the-art generative approaches for medical image inpainting due to their ability to generate anatomically consistent reconstructions. This survey presents a systematic review of diffusion-based methods for medical image inpainting, covering the main architectures, applications, datasets, and evaluation strategies reported across 60 studies. In addition, we propose a taxonomy for diffusion-based approaches. The analysis reveals a rapid growth of research interest in diffusion-based medical image inpainting, with denoising diffusion probabilistic models and latent diffusion models emerging as the dominant architectures. The reviewed studies mainly focus on artifact removal, data augmentation, pseudo-healthy tissue reconstruction, and anomaly detection, particularly in magnetic resonance imaging and computed tomography imaging. Overall, diffusion models demonstrate strong performance in producing anatomically plausible reconstructions and aiding downstream clinical tasks. However, the review also highlights important challenges, including the lack of standardized benchmarks, limited dataset diversity, and restricted validation procedures across diverse clinical applications and imaging scenarios.
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