直接用PPG预测血压比经ECG中转更准,适合可穿戴设备。
Blood Pressure Estimation from PPG: A Comparative Study of Direct and ECG-Mediated Deep Learning Pipelines

- 跳过ECG,直接从PPG信号预测血压
- 直接预测达英国高血压学会A级标准(收缩压误差4.82mmHg)
- 为可穿戴设备提供更简单高效的血压监测方案
连续无袖带血压监测对智能健康系统和可穿戴设备至关重要,有助于心血管疾病的早期发现、长期追踪与个性化管理。以往方法常通过从光电容积脉搏波(PPG)重建心电图(ECG)来间接估计血压,认为ECG与血压有更强生理关联。但本研究在MIMIC-III波形数据库上进行大规模相关性分析,发现PPG与动脉血压(ABP)的相关性显著强于ECG(|r|=0.247,p<0.001 vs r=0.018,p=0.187),挑战了该假设。基于此,我们系统比较了直接PPG-to-BP预测与ECG中介管道,使用多个先进深度学习模型,在3,127名患者的174万段数据上验证。结果表明,直接预测达到英国高血压学会A级性能(收缩压平均绝对误差4.82 mmHg,舒张压4.31 mmHg),优于所有基于ECG的方案(仅达B级)。研究证明,仅用可穿戴设备采集的PPG信号即可实现高精度连续血压监测,为真实场景下的智能健康系统提供更简洁高效的方法。
原文摘要 · Abstract (English)
Continuous cuffless blood pressure (BP) monitoring is essential for connected health systems and wearable devices, enabling early detection, longitudinal tracking, and personalized management of cardiovascular disease. Many prior approaches attempt to estimate BP indirectly by reconstructing electrocardiography (ECG) from photoplethysmography (PPG), assuming ECG provides a stronger physiological link to BP. However, ECG sensing is less accessible in wearable settings and may introduce unnecessary complexity. In this work, we first perform a large-scale physiological correlation analysis on the MIMIC-III waveform database, revealing that PPG exhibits substantially stronger coupling with arterial blood pressure (ABP) ($|r|=0.247$, $p<0.001$) than ECG does ($r=0.018$, $p=0.187$), challenging the assumption that ECG provides a superior intermediate representation. Motivated by this insight, we conduct a systematic comparison between direct PPG-to-BP prediction and ECG-mediated pipelines using multiple state-of-the-art deep learning models. Across 1.74M segments from 3,127 patients, direct PPG-to-BP prediction achieves British Hypertension Society Grade A performance ($\mathrm{MAE}_{\mathrm{SBP}} = 4.82 mmHg$, $\mathrm{MAE}_{\mathrm{DBP}} = 4.31 mmHg$), outperforming all ECG-mediated approaches, which achieve only Grade B accuracy. Our findings suggest that accurate continuous BP monitoring can be achieved directly from wearable PPG signals, enabling simpler, more efficient pipelines for real-world connected health systems.
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