arXiv:2607.25107cs.CRcs.LG2026-07中稿 · and presented at S…

基于微服务的联邦学习框架,保护基因组数据隐私并支持高效模型聚合。

MOSAIC-FL, a micro-service based privacy-preserving framework with application to genomics

论文配图:MOSAIC-FL, a micro-service based privacy-preserving framework with application to genomics
图 1 · 摘自论文原文
  • 采用gRPC与有限状态机实现组件同步与威胁检测。
  • 通过阈值CKKS同态加密,仅需t/N活跃客户端即可解密,通信开销低。
  • 适用于基因组分析等敏感领域,抗密钥恢复攻击,适合医疗数据协作。

安全与隐私是联邦学习在医疗和基因组学等领域的核心需求。本文提出MOSAIC-FL框架,采用模块化微服务架构,集成高效的gRPC通信层和有限状态机,保障组件同步与威胁检测。基于阈值版CKKS同态加密的容错安全聚合协议,使编排服务器可盲参与模型聚合,仅需t-out-of-N活跃客户端即可完成解密,同时通过密码学与网络协议降低通信开销。通过噪声注入实现IND-CPA-D安全,并每轮更新集体密钥材料以抵御近期同步解密器的密钥恢复攻击。实验涵盖标准图像识别(EMNIST)及复杂基因组分类任务,包括TCGA乳腺癌亚型分类,评估了不同阈值与模型规模下的系统性能。

原文摘要 · Abstract (English)

Security and privacy are primordial requirements for Federated Learning (FL), especially in fields such as healthcare and genomics where sensitive information has to be analyzed. Our FL framework is designed to address these challenges while proposing a modular, flexible and micro-service architecture. More precisely, it integrates an efficient gRPC communication layer and a Finite State Machine to ensure robust component synchronization and threat detection, while relying on a fault-tolerant secure aggregation protocol using a Threshold variant of the CKKS homomorphic cryptosystem. This allows blind model aggregation by an orchestration server, requiring a minimum of $t$-out-of-$N$ active clients for decryption while minimizing communication overhead thanks to both cryptographic and network protocols. We ensure IND-CPA-D security through noise flooding and mitigate the recent key-recovery attack on synchronized decryptors by renewing the collective key material at every round. We demonstrate the framework's effectiveness through diverse use cases, ranging from standard image recognition (EMNIST) to complex genomic classification including breast cancer subtyping on TCGA, evaluating system performance across different threshold values and model scales.

联邦学习隐私保护基因组分析同态加密

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