提出可实时运行的矩阵分解方法,解决医学影像处理速度瓶颈
Quasi-SVD: Learning a Lie-constrained matrix factorisation for real-time imaging

- 用李群参数化单因子保持正交性,实现完全并行化分解
- 重建质量SSIM达0.89-0.94,速度比cuSOLVER快3-20倍
- 适用于超声定位显微与神经外科组织分析等临床场景
奇异值分解(SVD)在计算成像中广泛应用,但其固有的串行性限制了实时GPU处理能力,难以部署于临床流程。本文提出Quasi-SVD,一种可微、完全并行化的矩阵分解框架。不强制双因子正交,仅对单一李群参数化因子保证精确正交,其余成分通过软约束恢复,避免迭代特征向量优化。该非对称设计在理论上足以保证分解有效性,实现SSIM = 0.89–0.94的重建保真度,较cuSOLVER和随机化SVD加速3–20倍,吞吐量超过25 FPS。在两类医学成像任务上验证:(1)超声定位显微中的时空背景剔除,需高维矩阵分离;(2)神经外科组织表征的穆勒矩阵偏振成像,需大批量小矩阵处理。在多种成像设备下均展现鲁棒域迁移能力,在临床规模矩阵上达到>25 FPS,满足实时图像引导工作流需求,而传统求解器无法支持。通过牺牲精确谱恢复来优先保障下游重建质量,使结构化矩阵分解真正适用于实时成像。
原文摘要 · Abstract (English)
Singular Value Decomposition (SVD) underlies matrix factorisation tasks across computational imaging, with medical applications increasingly demanding real-time processing. Yet SVD algorithms are inherently sequential, constraining real-time GPU throughput and limit online deployment in clinical pipelines. This study introduces Quasi-SVD, a differentiable, fully parallelized matrix factorization framework for GPUs. Rather than enforcing orthogonality on both factors, it guarantees exact orthogonality for a single Lie-parameterized factor while recovering the remaining components through soft constraints, enabling efficient parallel decomposition without iterative singular-vector optimization. This asymmetric design, provably sufficient for valid factorisation, achieves reconstruction fidelity of SSIM = 0.89-0.94 and accelerates computation by 3-20x relative to cuSOLVER and randomised SVD, enabling throughput above 25 FPS. Performance is evaluated on two medical imaging tasks spanning complementary computational regimes: (1) spatio-temporal background subtraction for ultrasound localisation microscopy, requiring high-dimensional matrix separation, and (2) Mueller matrix polarimetry for neurosurgical tissue characterisation, requiring massive batch processing of small matrices. Across both regimes and multiple imaging instruments, the proposed framework demonstrates robust domain transfer and throughput exceeding 25 FPS at clinical matrix scales, a rate sufficient for live image-guided workflows that classical solvers cannot currently support in these settings. By prioritising downstream reconstruction fidelity over exact spectral recovery, Quasi-SVD makes structured matrix factorisation practical for real-time imaging.
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