arXiv:2607.28327cs.CV2026-07中稿 · STACOM 2026

提出新指标评估冠脉分割连通性,提升FFR-CT决策准确性

Same Branches, Different Trees: A Bifurcation Connectedness Metric for Coronary Artery Segmentation and FFR-CT Decision Agreement

论文配图:Same Branches, Different Trees: A Bifurcation Connectedness Metric for Coronary Artery Segmentation and FFR-CT Decision Agreement
图 1 · 摘自论文原文
  • 设计分叉连通性评分BCS,精准捕捉分割中的局部断开问题
  • 高BCS值对应FFR-CT决策一致性提升,严重病变下优势更明显(OR 2.16)
  • 建议同时报告分支恢复与连通性指标,避免误判几何精度

基于CT血管造影的血流储备分数(FFR-CT)通过患者特异性血管模型模拟血流,其准确性不仅依赖体积重叠,更取决于分割树的连通性:即使Dice分数高,若在分叉处断开下游分支,仍会导致治疗决策错误。现有拓扑感知损失如clDice和骨骼召回率作用于全局中心线,可能忽略局部断开。本文研究分叉连通性评分(BCS),该指标在每个真实分叉处评估连通性,并引入可微训练的soft-BCS。BCS能捕捉标准指标遗漏的分割质量特征:对连通性断裂敏感,而对保持连通性的狭窄不敏感。更高的BCS值伴随同一求解器在预测与真实几何上作出的FFR-CT决策更一致,尤其在严重病变中(比值比2.16,95%置信区间[1.23, 4.18])。二者来自同一求解器,反映的是几何保真度而非临床差异。训练中,soft-BCS与骨骼召回率虽恢复相同分支,但构建不同树结构。分支恢复与连通性是可分离属性,因此建议分别报告衡量指标。

原文摘要 · Abstract (English)

Fractional flow reserve derived from CT angiography (FFR-CT) simulates flow through a patient-specific vessel model, so its accuracy depends on the connectedness of the segmented tree, not only on volumetric overlap: a segmentation can reach high Dice yet sever a bifurcation, dropping the downstream subtree and reversing the treatment decision. Topology-aware losses such as clDice and Skeleton Recall act on the global centreline and can miss localised breaks. We study the Bifurcation Connectedness Score (BCS), which scores connectedness at each ground-truth bifurcation, and soft-BCS, its differentiable training surrogate. BCS captures a property of segmentation quality the standard metrics miss: it responds strongly to breaks in connectedness while staying largely unchanged under connectedness-preserving narrowing. Higher BCS accompanies closer agreement between the FFR-CT decisions a solver makes on predicted versus ground-truth geometry, most clearly in severe disease (OR 2.16, CI [1.23, 4.18]). Both decisions come from the same solver, so this reflects geometric, not clinical, fidelity. In training, soft-BCS and Skeleton Recall recover the same branches but build different trees. Recovering branches and keeping them connected are separable properties, so we recommend reporting a measure of each.

医学图像冠脉分割连通性评估FFR-CT

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