通过原型引导校准正负证据，提升高光谱图像分类可靠性。

In real-world hyperspectral scenes, pixel representations are often ambiguous due to factors such as spectral similarity, mixed pixels, and local context interference, which may simultaneously encode discriminative evidence and interfering information. Existing methods mainly focus on learning more powerful representations or modeling broader contexts, but rarely investigate whether the learned representations provide reliable evidence or introduce interference into classification decisions. To address this issue, we view hyperspectral image classification from the perspective of pixel-level evidence reliability modeling and propose PNEC-Mamba, a prototype-guided positive-negative evidence calibration framework. The framework progressively establishes semantic references, separates class-related evidence from interference, estimates pixel-level reliability, and performs selective calibration. First, a full-image state-space encoder extracts pixel representations, while dynamic class prototypes provide semantic references that evolve jointly with the feature space. Subsequently, positive and negative evidence is derived from pixel-prototype competition, explicitly separating discriminative cues that support classification from confusing signals associated with competing classes. Based on these evidence relationships, a multi-source uncertainty estimation strategy is introduced to assess pixel-level reliability, enabling stronger evidence calibration for uncertain regions. Finally, a full-resolution consistency refinement step is applied to recover local spatial details and improve boundary coherence in the final predictions. Extensive experiments on three benchmark datasets demonstrate that PNEC-Mamba achieves superior classification performance compared with state-of-the-art methods.