构建分层诊断框架,让模型像医生一样由整体到局部判断胸片异常。
Clinically-Grounded Hierarchical Classification for Consistent Chest X-ray Interpretation

- 采用三层临床分层结构,从9个解剖区域到28种病灶联合建模。
- 在多个层级上优化预测一致性,准确率超越传统方法。
- 适合医学影像分析、临床辅助诊断等场景使用。
准确的胸部X光解读具有天然的层次性。临床决策不仅关注是否存在异常,还依赖其解剖位置,需从宏观解剖系统逐步推导至具体病理发现。然而现有自动化系统多将其视为平坦分类问题,未能捕捉层级间依赖或保证粗粒度与细粒度预测的一致性。本文提出CHASE(Hierarchical Analysis and Structured Enforcement),一种统一的单阶段框架,通过临床驱动的三层分类体系——9个解剖区域、17个子区域、28种病理发现——模拟放射科医生由粗到细的推理过程。该框架在共享视觉变压器主干网络中联合优化多层级监督、跨层级概率对齐及层级违反惩罚机制,确保细粒度病灶预测均得到粗粒度解剖上下文支持,而非孤立预测。实验表明,CHASE在所有层级上均优于平坦与分层基线,且概率层次一致性显著提升;各层级注意力图进一步验证了预测结果的解剖合理性。代码已开源:https://github.com/yejix-ai/CHASE。
原文摘要 · Abstract (English)
Accurate chest X-ray interpretation is inherently hierarchical. Clinical decisions depend not only on what abnormality is present but where it is situated, requiring reasoning from broad anatomical systems down to specific pathological findings. Yet existing automated systems largely treat this as a flat classification problem, failing to capture inter-level dependencies or enforce coherence between coarse and fine predictions. We propose CHASE (Classification with Hierarchical Analysis and Structured Enforcement), a unified single-stage framework that mirrors radiologists' coarse-to-fine reasoning through a clinically driven three-level taxonomy of 9 anatomical regions, 17 sub-regions, and 28 pathological findings. CHASE jointly optimizes multi-level supervision, cross-level probability alignment, and a hierarchy-violation penalty within a shared Vision Transformer backbone. This ensures that fine-grained findings are anatomically supported by their coarser-level context rather than predicted in isolation. Experiments demonstrate that CHASE outperforms flat and hierarchical baselines across all levels while achieving superior probabilistic hierarchy consistency, with level-wise attention maps confirming anatomically grounded predictions. Code is available at: https://github.com/yejix-ai/CHASE.
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