arXiv:2608.03107cs.CV2026-08

一个统一模型搞定不同光路配置的激光扫描成像融合,自动适配分辨率差异。

A Unified Resolution-Conditioned Framework for Orthogonal Line-Scanning Image Fusion

论文配图:A Unified Resolution-Conditioned Framework for Orthogonal Line-Scanning Image Fusion
图 1 · 摘自论文原文
  • 用可调节的特征调制机制,让单一模型适应多种狭缝宽度配置。
  • 在多配置下均实现34-40 dB PSNR,远超独立模型和无条件训练。
  • 适合需要跨配置通用、高精度图像融合的显微成像研究者使用。

激光线扫描显微镜能实现快速三维成像,但横向分辨率具有各向异性。正交线扫描提供互补方向信息,可恢复近似各向同性分辨率,但现有深度学习方法需为每种光学配置单独建模。本文提出一种基于秩增强线性注意力(RELA)的统一、分辨率条件化融合框架。通过特征级线性调制(FiLM)连续地以分辨力比为条件,使单一模型可适应不同狭缝宽度。进一步引入自适应RELA,用比例条件化的多尺度深度卷积替代固定核秩增强,并采用可学习的注意力温度随退化程度调节选择性。训练数据通过物理基础的可分离点扩散函数模型生成,与实测光学数据验证一致,达到48.3 dB精度。所提模型在多种配置下均取得34-40 dB PSNR;而无条件多狭缝训练仅达24.3 dB,单配置专用模型在未见设置下损失4-9 dB。模型还能平滑泛化至未见中间配置,无插值伪影。消融实验表明,FiLM缓解配置歧义,全局线性注意力捕捉长程方向对应关系,自适应温度在近各向同性条件下额外提升2 dB性能,此时互补信号较弱。

原文摘要 · Abstract (English)

Laser line-scanning microscopy enables fast volumetric imaging but produces anisotropic lateral resolution. Orthogonal line scans provide complementary directional information that can recover near-isotropic resolution, yet existing deep-learning methods require a separate model for each optical configuration. We present a unified, resolution-conditioned fusion framework based on Rank Enhanced Linear Attention (RELA). Feature-wise Linear Modulation (FiLM) conditions the network continuously on the resolving-power ratio, enabling one model to adapt across slit widths. We further introduce Adaptive RELA, which replaces fixed-kernel rank enhancement with ratio-conditioned multi-scale depthwise convolutions and uses a learnable attention temperature to adjust selectivity with degradation severity. Training data spanning multiple slit configurations are generated using a physics-grounded separable point-spread-function model verified against measured optical data at 48.3 dB accuracy. The resulting model achieves 34-40 dB PSNR across configurations, whereas unconditioned multi-slit training collapses to 24.3 dB and per-slit specialists lose 4-9 dB outside their training setting. It also generalizes smoothly to unseen intermediate configurations without interpolation artifacts. Ablations show that FiLM resolves configuration ambiguity, global linear attention captures long-range directional correspondences, and adaptive temperature yields an additional 2 dB in the challenging near-isotropic regime, where complementary signals are weak.

图像融合显微成像深度学习分辨率自适应

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