通过智能选样与提前预测,提升医学图像分割的可靠性。
Context Matters: Support Set Selection and Failure Detection for In-Context Medical Image Segmentation

- 基于图像相似性选择支持集,优于随机采样。
- 小样本下性能提升显著,最大增益达40%以上。
- 可提前预判分割失败,适合临床部署场景。
上下文学习(ICL)通过任务特定的支持集(图像-掩码示例)实现医学图像分割模型对未见结构和模态的零样本适配。由于支持集是模型唯一的任务信号,其构成直接影响分割性能。本文研究支持集作为可控变量对ICL可靠性的影响:首先比较随机采样与基于视觉相似性的选择方法;其次训练一个基于Transformer的分类器,仅凭查询图像和候选支持图像,预测分割结果是否低于指定的交并比(IoU)阈值。在四个基准数据集、三种成像模态上使用MultiverSeg与DINOv3嵌入进行实验表明,相似性选择始终优于或等同于随机采样,尤其在支持集最小时效果提升最显著。此外,该分类器在所有四个基准上均能高于随机水平预测分割失败。结果表明,通过有意识地选择支持集并提前预判失败,可显著提升医学图像分割的可靠性,为临床安全应用提供实用机制。
原文摘要 · Abstract (English)
In-context learning (ICL) adapts medical image segmentation models to unseen structures and modalities without retraining by conditioning on a task-specific support set of image-mask exemplars. Because this support set is the model's only task-specific signal, its composition directly influences segmentation performance. In this work, we investigate the support set as a controllable determinant of ICL reliability. First, we compare random sampling against similarity-based selection, where exemplars are retrieved based on their visual similarity to the query image. Second, we train a transformer-based classifier to predict, from the query and support images alone, whether a segmentation will fall below a specified Intersection-over-Union (IoU) threshold. Using MultiverSeg with DINOv3 embeddings across four benchmarks and three imaging modalities, we show that similarity-based selection consistently matches or outperforms random sampling, with the largest gains at the smallest support set sizes. Furthermore, our classifier predicts segmentation failure above chance on all four benchmarks. Ultimately, these results demonstrate that the reliability of in-context segmentation can be both improved via informed support selection and anticipated before use, providing practical mechanisms for safer clinical deployment.
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