跨场强MRI图像生成,无需配对数据即可保留解剖结构
Task-Adaptive 3D Cross-Field MRI Translation via Field-Conditioned Content-Style Pretraining

- 通过内容-风格解耦预训练,实现多场强间3D MRI图像迁移
- 在0.1T到7T五种场强上验证,生成图像保持三维解剖结构
- 适合医学影像领域研究人员,尤其关注场强差异问题
磁共振成像(MRI)中磁场强度是导致域偏移的主要因素,影响信噪比、组织对比度、空间细节和解剖边界可见性。MRIxFields 2026挑战赛聚焦于0.1T、1.5T、3T、5T和7T场强间的跨场强图像翻译,包含任意场强到7T、0.1T到高场强、任意场强到任意场强三种任务,要求生成目标场强图像特征的同时保留个体解剖结构。由于同一样本在多场强下的配对数据极少,训练困难。本文提出基于场强条件化内容-风格预训练的3D无配对跨场强MRI翻译框架。该框架首先通过解耦解剖内容与场强相关对比特征,学习所有可用场强间的可控场强转换。预训练主干模型随后适配特定任务目标域。模型包含3D内容编码器、3D风格编码器、场强条件化风格生成器、AdaIN调制解码器和多场强判别器。对抗学习促进目标场强外观的真实性,而循环一致性、身份、内容、风格和多样性约束则保障解剖保真度与可控生成。在覆盖五种场强和三种MRI模态的MRIxFields数据集上评估,配对测试结果显示,该框架可适应三项挑战设置,并在合成体积中保持三维解剖结构。代码已公开于https://github.com/Idea89560041/3D-MRI-Field-Translation。
原文摘要 · Abstract (English)
Magnetic field strength is a major source of domain shift in magnetic resonance imaging (MRI), affecting signal-to-noise ratio, tissue contrast, spatial detail, and the visibility of anatomical boundaries. The MRIxFields 2026 challenge investigates this problem through cross-field MRI translation across acquisitions at 0.1T, 1.5T, 3T, 5T, and 7T. Its three tasks, Any-to-7T, 0.1T-to-High, and Any-to-Any synthesis, require the generation of target-field image characteristics while preserving subject-specific anatomy. This problem is particularly challenging because paired acquisitions of the same subject across multiple field strengths are rarely available for training. We propose a 3D unpaired cross-field MRI translation framework based on field-conditioned content-style pretraining. The proposed framework first learns controllable field-to-field translation across all available field strengths by disentangling anatomical content from field-dependent contrast characteristics. The pretrained backbone is then adapted to task-specific target domains. Our model comprises a 3D content encoder, a 3D style encoder, a field-conditioned style generator, an AdaIN-modulated decoder, and a multi-field discriminator. Adversarial learning encourages realistic target-field appearance, while cycle-consistency, identity, content, style, and diversity constraints promote anatomical fidelity and controllable translation. We evaluate the proposed method on MRIxFields data spanning five field strengths and three MRI modalities. Experiments on paired test data demonstrate that the framework can adapt to the three challenge settings while preserving three-dimensional anatomical structure in the synthesized volumes. The implementation code is publicly available at https://github.com/Idea89560041/3D-MRI-Field-Translation.
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