提出三维CT生成的条件分类框架,系统梳理研究设计空间。
Knowledge-Guided 3D CT Generation: A Conditioning-Centric Taxonomy

- 按外部知识类型、融合方式、生成架构三维度分类
- 构建K×I×A设计空间,统一现有方法视角
- 揭示研究空白,指导未来方向
可控生成需依赖外部知识以实现对语义内容、结构属性和变化性的显式约束。在三维计算机断层扫描(3D CT)中,这种控制对临床应用至关重要,包括数据增强、隐私保护的数据共享以及特定解剖或病理场景的模拟。尽管条件化3D CT生成研究迅速发展,但方法多样性导致系统比较困难,并掩盖了根本设计选择。本文提出一种以条件为中心的分类体系,从三个正交维度组织文献:外部知识类型(K)、知识融合范式(I)和生成架构(A)。该分解定义了一个明确的设计空间(K×I×A),为先前工作提供统一视角。基于此框架,系统梳理现有方法,识别主导趋势与重复设计模式,并指出未充分探索的设计空间区域,指向未来有前景的研究方向。
原文摘要 · Abstract (English)
Controllable generation guided by external knowledge is a key requirement in modern generative deep learning applications, enabling the synthesis of samples with explicit constraints on semantic content, structural properties, and variability. In 3D Computed Tomography (CT), such control is essential for clinical applications, including data augmentation, privacy-preserving data sharing, and the simulation of specific anatomical or pathological scenarios. While research on conditional 3D CT generation has expanded rapidly, the diversity of existing approaches makes systematic comparison difficult and obscures fundamental design choices. In this survey, we propose a conditioning-centric taxonomy that organizes the literature along three orthogonal dimensions: the type of external knowledge (K), the knowledge integration paradigm (I), and the generative architecture (A). This factorization defines an explicit design space (K x I x A) that provides a unified perspective on prior work. Using this framework, we systematize existing methods, identify dominant trends and recurring design patterns, and highlight underexplored regions of the design space that point toward promising directions for future research.
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