用声纹轮廓合成训练数据，提升小鼠叫声去噪效果

Bioacoustic recordings are often degraded by ambient noise, which complicates the analysis of weak or noise-overlapped vocalizations. Convolutional neural networks, particularly U-Net architectures, have shown a strong denoising performance in speech and music processing. However, their direct application to bioacoustic signals is limited by the scarcity of clean training data. To address this issue, we propose a training set synthesis approach and develop a supervised denoising model that predicts a complex ratio mask in the time-frequency domain. The model leverages ridges, or frequency contours, that represent the fundamental frequency together with one or more harmonic partial components of vocalizations. These ridges are used both for the synthesis of training sets and to design a loss function that assigns higher weights to the ridge regions (ridge-guided loss function). This weighting step helps the network better preserve vocalization details during denoising. As a case study, we evaluate our approach using ultrasonic vocalizations (USVs) recordings of house mice, which are widely studied in behavioral biology and neuroscience. In actual field recordings, the proposed method enhances fundamental and harmonic partial ridge tracking compared to our previous signal-processing approach. In addition, a classifier trained on denoised data improves USV classification on out-of-sample, noisy recordings from wild and domesticated mice compared to classifiers trained on noisy recordings. Our proposed method also substantially improves the scale-invariant signal-to-distortion ratio on synthetic testing data across a wide range of input signal-to-noise ratios. Although we focus on USVs, the proposed approach should be broadly applicable to other bioacoustic signals with trackable ridges, and thus enables ridgebased training set synthesis and denoising.