arXiv:2608.18451cs.LGq-bio.QM2026-08

用自适应码本实现任意导联心房颤动检测,抗噪能力强。

Atrial Fibrillation Detection with Arbitrary Leads via a Codebook-Based Reconstruction-Classification Framework

论文配图:Atrial Fibrillation Detection with Arbitrary Leads via a Codebook-Based Reconstruction-Classification Framework
图 1 · 摘自论文原文
  • 基于双码本的重建-分类框架,学习抗噪声心电特征。
  • 跨数据集泛化性能优异,所有场景AUC均超0.98。
  • 适合真实临床环境,对基线漂移等干扰有强鲁棒性。

由于导联配置不一、跨数据集域偏移及生理与技术伪影普遍存在,从心电图(ECG)信号中可靠检测心房颤动(AF)在真实临床环境中仍具挑战。为此,我们开发了一种稳健且可泛化的深度学习模型用于精准AF检测。提出双重码本图协同网络(DCGCNet),一种端到端向量量化变分自编码器,联合执行AF分类与心电图重建。DCGCNet引入两个关键组件:(1) 局部-全局对比模块,用于学习抗噪声表示;(2) 自适应码本向量量化器,动态优化码本原型以更好地匹配输入数据分布,防止码本坍缩并提升泛化能力。DCGCNet在标准12导联内部数据集评估中达到当前最优性能,并在七个不同设置下展现卓越跨数据集泛化能力,所有情况下AUC均高于0.98。此外,在包含基线漂移、工频干扰和肌电伪影的真实噪声条件下仍保持高诊断准确率。结论:DCGCNet为鲁棒、可泛化、抗噪声的AF检测建立了新基准,具有在真实临床环境中部署的强大潜力。

原文摘要 · Abstract (English)

\textbf{Background and Objective}: Reliable atrial fibrillation (AF) detection from electrocardiogram (ECG) signals remains challenging in real-world clinical settings due to variable lead configurations, cross-dataset domain shifts, and pervasive physiological and technical artifacts. So we develop a robust and generalizable deep learning model for accurate AF detection.\\ \textbf{Methods}: We propose the Dual-Codebook Graph Collaborative Network (DCGCNet), a novel end-to-end vector-quantized variational autoencoder that jointly performs AF classification and ECG reconstruction. DCGCNet introduces two key components: (1) a Local-Global Contrastive Module for learning noise-invariant representations, and (2) an Adaptive Codebook Vector Quantizer that dynamically refines codebook prototypes to better align with input data distributions, thereby preventing codebook collapse and enhancing generalization.\\ \textbf{Results}: DCGCNet achieves state-of-the-art performance in standard intra-dataset 12-lead evaluation and demonstrates exceptional cross-dataset generalization across seven diverse settings, consistently attaining AUC > 0.98 in all cases. Furthermore, it maintains high diagnostic accuracy under realistic noisy conditions, including baseline wander, powerline interference, and EMG artifacts.\\ \textbf{Conclusions}: DCGCNet establishes a new benchmark for robust, generalizable, and noise-resilient AF detection, showing strong potential for deployment in real-world clinical environments.

心电分析心房颤动抗噪检测深度学习

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