用变化点检测评估和校准PPG血压估计,提升动态波动下的准确性
Change Point--Aware Evaluation and Re-Calibration of PPG-Based Blood Pressure Estimation

- 基于时间序列变化点检测识别血压突变时刻,替代人工阈值判断
- 发现主流模型在血压突变时误差显著上升,周期性校准无效
- 仅在检测到变化点时触发针对性重校准,无需修改模型结构
基于光体积脉搏波图(PPG)的无创连续血压监测是袖带测量的有前景替代方案。然而,现有研究多依赖整个评估时段的聚合性能指标(如平均绝对误差),难以揭示快速血压波动期间的模型失效,限制了临床相关性。本文提出一种基于时间序列变化点检测的波动感知评估框架,通过捕捉血压轨迹的突发分布偏移来识别血压变化点,而非依赖启发式阈值(如ΔBP > 10 mmHg)。分析表明,多个先进模型在血压变化点附近性能显著下降,且周期性测试时校准无法应对此类动态变化。为此,我们引入一种由检测到的变化点触发的定向重校准框架,在不修改模型架构的前提下提升鲁棒性。据我们所知,这是首个从血压变化点视角系统评估PPG血压估计的工作,强调了波动感知评估与校准对真实连续血压监测的重要性。
原文摘要 · Abstract (English)
Non-invasive continuous blood pressure (BP) monitoring using photoplethysmography (PPG) is a promising alternative to cuff-based measurements. However, existing PPG-based BP estimation studies predominantly rely on aggregated performance metrics (e.g., mean absolute error) computed over entire evaluation intervals, which can obscure model failures during rapid BP fluctuations and limit clinical relevance. In this work, we propose a fluctuation-aware evaluation framework for PPG-based BP estimation based on time-series change point detection. Instead of heuristic BP thresholding (e.g., $Δ\mathrm{BP} > 10\mathrm{mmHg}$), we identify BP change points by capturing abrupt distributional shifts in BP trajectories and evaluate estimation performance specifically during these fluctuation periods. Our analysis shows that several state-of-the-art models exhibit substantial performance degradation around BP change points, and that periodic test-time calibration is insufficient to handle such dynamic BP variations. To address this limitation, we introduce a targeted re-calibration framework triggered by detected BP change points, improving robustness without modifying model architectures. To the best of our knowledge, this is the first systematic evaluation of PPG-based BP estimation from a BP change point perspective, highlighting the importance of fluctuation-aware evaluation and calibration for real-world continuous BP monitoring.
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