arXiv:2608.18986cs.CV2026-08中稿 · SWITCH+ 2026, a MI…

用多视角动态深度学习自动评估脑卒中侧支循环,提升评分一致性。

X-LMC: Cross-View Spatiotemporal Collateral Circulation Scoring from DSA

论文配图:X-LMC: Cross-View Spatiotemporal Collateral Circulation Scoring from DSA
图 1 · 摘自论文原文
  • 融合双视角时间序列血管造影,通过跨视图注意力建模血流动力学。
  • 在134例患者上达到QWK 0.398,优于基线模型(0.322)。
  • 首个自动化侧支循环评分框架,适合脑卒中临床研究与智能诊断。

数字减影血管造影(DSA)是硬膜外侧支循环(LMC)评估的金标准,为治疗策略制定、神经康复规划和卒中回顾研究提供关键预后信息。然而,临床中基于ASITN/SIR标准的分级依赖人工主观判读,结果差异大。本文提出X-LMC,一种从动态双平面DSA自动评分侧支循环的时空框架。该架构采用DINOv2提取空间帧特征,通过令牌级跨视图注意力融合正交投影,并使用递归网络建模造影剂动态变化。在包含134例M1段闭塞患者的多中心数据集上进行5折交叉验证,X-LMC的点估计优于静态架构及现有时空基线,在二次加权克劳斯卡系数(QWK)达0.398(基线0.322),二分类宏平均F1得分为0.711(基线0.663)。其性能与临床医生间一致性(QWK: 0.314)相近。本研究首次实现DSA侧支循环自动化评分,证明多视角时序深度学习可捕捉特异性血流动态,为卒中队列客观血流表型分析奠定可复现基础。代码已开源:https://github.com/maedehafezi/X-LMC。

原文摘要 · Abstract (English)

Digital subtraction angiography (DSA) is the reference standard for leptomeningeal collateral (LMC) assessment, providing critical prognostic insights to guide secondary treatment strategies, neurorehabilitation planning, and retrospective stroke research. However, clinical LMC grading via the ASITN/SIR scale relies on manual, highly variable visual inspection. We introduce X-LMC, a spatiotemporal framework for automated collateral scoring from time-resolved biplane DSA. The proposed architecture encodes spatial frame representations through a DINOv2 backbone, fuses orthogonal projections via a token-level cross-view attention module, and models representations of contrast bolus dynamics using a recurrent network architecture. We evaluate our framework on a multicenter dataset of 134 patients with M1-segment occlusions. In a 5-fold cross-validation setting, X-LMC yields higher point estimates than static architectures and spatiotemporal baselines adapted from related angiographic tasks, achieving a Quadratic Weighted Kappa (QWK) of 0.398 (vs. 0.322) and a dichotomized macro-F1 score of 0.711 (vs. 0.663) against the best-performing baseline. X-LMC performance also aligns with the observed clinical inter-rater agreement (QWK: 0.314). As the first DSA study attempting to automate LMC scoring, we demonstrate that multi-view temporal deep learning can capture collateral-specific contrast kinetics. Ultimately, these benchmarks delineate the clinical ambiguities and achievable performance boundaries of automated ASITN/SIR grading, establishing a reproducible foundation for objective hemodynamic phenotyping in stroke cohorts. Code is available at https://github.com/maedehafezi/X-LMC.

脑卒中侧支循环深度学习医学影像

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