arXiv:2608.24025cs.CV2026-08

用低秩速度场约束医学影像插值,让中间帧更真实稳定。

Low-Rank Velocity Fields as a Structural Prior for Unsupervised 4D Medical Image Interpolation

论文配图:Low-Rank Velocity Fields as a Structural Prior for Unsupervised 4D Medical Image Interpolation
图 1 · 摘自论文原文
  • 引入低秩速度场结构先验,分解运动为共用基底与个体核心。
  • 在ACDC和4D-Lung数据集上达到领先性能,边界更清晰。
  • 适合需要高质量无监督动态医学影像的科研与临床应用。

仅用起始和结束体积进行无监督4D医学图像插值时,因约束弱常导致中间帧边界不稳定、运动不生理,影响可解释性与下游分析。本文提出低秩速度场作为结构先验,将运动限制在张量分解的低秩速度场空间中,分解为全局共享的空间基底与紧凑的样本特异核,促进空间相关、解剖一致的形变,抑制体素级高频伪影。采用从粗到细的多尺度建模方案,推理时组合各尺度形变以生成任意时间点的体积。理论分析表明,在张量参数化下,低秩参数控制速度场的平滑能量,解释了为何低秩建模能产生更平滑的运动。在ACDC与4D-Lung数据集上的实验表明,本方法达到当前最优性能,即使在无中间帧监督的情况下,仍优于多数现有方法,生成的中间帧具有更高的结构一致性与更稳定的解剖轮廓。

原文摘要 · Abstract (English)

Endpoint-only unsupervised 4D medical image interpolation synthesizes intermediate volumes from sparsely sampled sequences with only the start and end volumes available for training; however, this weakly constrained setting often yields intermediates with unstable boundaries and non-physiological motion, limiting interpretability and downstream analysis. We propose low-rank velocity fields as a structural prior, constraining motion to a structured Tucker low-rank velocity field space that decomposes motion into globally shared spatial bases and a compact sample-specific core, thereby encouraging spatially correlated, anatomy-consistent deformation while suppressing voxel-wise high-frequency artifacts. To capture global coordination and local non-rigid details, we model motion in a coarse-to-fine multi-scale scheme and compose scale-wise deformations at inference to synthesize volumes at arbitrary times. We further provide a theoretical analysis showing that, under Tucker parameterization, low-rank parameters control the smoothness energy of the velocity field, explaining why low-rank modeling promotes smoother motion. Experiments on ACDC and 4D-Lung demonstrate state-of-the-art performance, remaining competitive with methods trained with intermediate-frame supervision, and producing intermediates with improved structural coherence and more stable anatomical contours.

医学图像无监督学习4D插值低秩模型

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