用解剖先验和病例原型监督,提升胎儿超声盲扫标准切面检测准确率
Anatomy-Guided Foundation Model Adaptation with Within-Case Prototype Supervision for Standard Plane Detection in Fetal Ultrasound Blind Sweeps

- 通过解剖加权池化与病例原型损失,引导冻结的医学视觉模型聚焦关键区域
- 在ACOUSLIC-AI上达到67.72的测试F1,比最强基线高出13.20点
- 特别适合低资源环境下胎儿超声自动定位,对小样本、不平衡数据敏感
在低成本产科盲扫中检测胎儿腹围标准切面是一个高度不平衡的帧分类问题:正样本帧占比不足3%,且呈短段连续分布,现有超声与视觉基础模型难以有效处理。本文提出AnatoProto,一种轻量级序列级框架,通过四个组件适配冻结的BiomedCLIP编码器:(i) 解剖加权空间池化,利用nnU-Net获取的腹部区域概率作为空间先验,重新加权BiomedCLIP的补丁令牌,使冻结的语义特征集中于解剖学有意义区域;(ii) 案例内原型损失,将每帧嵌入拉向同次扫描中正样本帧的均值,利用帧级不可见的病例级结构;(iii) 三阶段级联精修(帧→段→案例级拒判器),将预测单位从噪声帧提升至结构约束段;(iv) 混合预测头,联合建模帧内稳定性与帧间边界变化,抑制边界误报。在ACOUSLIC-AI基准上,AnatoProto测试F1达67.72,优于最强基础模型基线(FetalCLIP + PRS,F1=54.52)13.20点,优于最强视频时序动作检测基线(TriDet + PRS)15.76点。协同性研究显示,原型损失与解剖加权池化非可加:单独使用原型损失使召回率下降12点,但结合解剖加权池化后召回率提升6.5点——这一符号反转归因于病例原型的准确性。
原文摘要 · Abstract (English)
Detecting the fetal abdominal circumference standard plane in low-cost obstetric blind sweeps is a highly imbalanced frame-classification problem: positive frames account for under 3% of a sequence, form short contiguous segments, and are poorly handled by off-the-shelf ultrasound and vision foundation models. We propose AnatoProto, a lightweight sequence-level framework that adapts a frozen BiomedCLIP encoder to fetal blind sweeps through four components: (i) anatomy-weighted spatial pooling that uses nnU-Net abdominal-region probabilities as a spatial prior to reweight BiomedCLIP patch tokens, so frozen semantic features are aggregated onto anatomically meaningful regions; (ii) a within-case prototype loss that pulls each frame embedding toward the mean of positive frames of the same sweep, exploiting case-level structure unavailable at the frame level; (iii) a three-stage cascade refinement (frame->segment->case-level rejecter) that lifts the prediction unit from noisy frames to structurally-constrained segments; and (iv) a hybrid prediction head that jointly models per-frame stability and inter-frame boundary transitions to suppress boundary false positives. On the ACOUSLIC-AI benchmark, AnatoProto reaches a test F1 of 67.72, outperforming the strongest foundation-model baseline (FetalCLIP + PRS, F1 = 54.52) by +13.20 F1 and the strongest video temporal-action-detection baseline (TriDet + PRS) by +15.76 F1. A synergy study, backed by embedding geometry and paired-bootstrap confidence intervals, shows that the prototype loss and anatomy-weighted pooling are not additive: applied alone the prototype loss reduces recall by 12 points, but combined with anatomy-weighted pooling it increases recall by 6.5 points -- a sign-flip we trace to the accuracy of the within-case prototype.
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