用提示引导模型交互式分割肺部间质病,提升诊断精度。
Prompt-Guided Interactive Segmentation of Interstitial Lung Disease in Thoracic CT

- 用框、点、自由画线等提示引导模型迭代优化分割结果。
- 全模型微调后平均Dice得分提升4.7个百分点,框提示效果最佳。
- 首次实现基于MedSAM2的3D肺部疾病交互分割,适合放射科医生使用。
准确分割间质性肺病(ILD)模式对定量评估和长期监测至关重要。现有方法受限于密集标注且生成静态结果无法修正,亟需交互式方案。尽管可提示模型在交互分割中展现潜力,其在ILD中的应用仍基本空白。为此,本文研究提示引导的基础模型用于ILD精修,首次将MedSAM2适配至胸部CT的3D ILD交互分割。考察三种微调策略与多种临床相关提示(边界框、点、自由画线、涂鸦)。在涵盖七种ILD模式及健康肺组织的数据集上,全模型微调表现最优,平均Dice分数较MedSAM2提升4.7个百分点。边界框提示性能最强,非原生的自由画线与涂鸦提示亦有效。最后,提出并评估一个端到端工作流:以自动分割为初始,再由放射科医生通过提示进行精修。模型权重与插件已开源:https://github.com/AIHNlab/ILD-SemiSegTool。
原文摘要 · Abstract (English)
Accurate segmentation of interstitial lung disease (ILD) patterns is essential for quantitative disease assessment and longitudinal monitoring. However, existing approaches remain limited by relying on dense annotations and producing static predictions that cannot be refined, motivating interactive approaches. While promptable models show promise in interactive segmentation, their adaptation to ILDs remains largely unexplored. To address this gap, we investigate prompt-guided foundation models for ILD refinement and present, to the best of our knowledge, the first adaptation of MedSAM2 for interactive 3D ILD segmentation on thoracic CT. We investigate three fine-tuning strategies and multiple clinically motivated prompts: bounding-boxes (BBox), point, lasso, and scribble. On a dataset spanning seven ILD patterns and healthy lung tissue, full model fine-tuning performed best, improving the average Dice score by 4.7 percentage points over MedSAM2.While BBox prompts achieve the strongest performance, non-native MedSAM2 interactions such as lasso and scribble prompts also prove effective. Finally, we present and evaluate a proof-of-concept end-to-end workflow in which MedSAM2 is initialized from an automatic segmentation prior and subsequently refined using radiologist prompts. Model weights and plug-ins made available at: https://github.com/AIHNlab/ILD-SemiSegTool.
Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。