arXiv:2608.30458cs.CV2026-08

跨机构联合分割肿瘤并分类浸润性膀胱癌,无需集中数据。

Federated Multi-Task Learning for Bladder Tumor Segmentation and MIBC Classification Using a Hybrid CNN-Transformer Architecture

论文配图:Federated Multi-Task Learning for Bladder Tumor Segmentation and MIBC Classification Using a Hybrid CNN-Transformer Architecture
图 1 · 摘自论文原文
  • 用混合卷积与注意力结构联合学习肿瘤分割和分期分类。
  • 联邦训练下分割DSC达0.8100,分类AUC达0.8931,综合得分0.8474。
  • 适合多中心医疗模型协作,保护患者数据隐私。

准确的膀胱肿瘤分割及肌层浸润性评估对治疗方案制定至关重要,但因患者数据无法集中且影像特征受扫描仪与协议差异影响,跨机构模型构建困难。本文提出一种跨四个临床中心的联邦多任务学习框架,用于联合实现膀胱肿瘤分割与肌层浸润性膀胱癌(MIBC)/非肌层浸润性膀胱癌(NMIBC)分类。所提Swin Hybrid模型结合ResNet-34分支提取局部纹理与边界信息,以及Swin-Tiny Transformer捕捉全局解剖上下文,并引入分割引导的分类机制,利用肿瘤定位信息辅助MIBC预测。同时,在中心化与联邦训练下探索多种增强策略以提升对多中心变异的鲁棒性。在FedBCa数据集上的实验表明,Swin Hybrid在评估架构中表现最佳,具有最优的分割与分类平衡。联邦训练下,Geo+Elastic增强使分割骰子系数(DSC)达到0.8100,患者级分类AUC为0.8931,综合得分最高为0.8474。结果证明,通过联邦学习可在不集中患者数据的前提下有效实现跨机构的联合分割与分类。

原文摘要 · Abstract (English)

Accurate bladder tumor segmentation and assessment of mus- cle invasion from T2-weighted MRI are important for treatment plan- ning, but developing robust models across institutions is challenging be- cause patient data cannot be centrally pooled and imaging characteristics vary across scanners and acquisition protocols. We propose a federated multi-task learning framework for joint bladder tumor segmentation and MIBC/NMIBC classification across four clinical centers. The proposed Swin Hybrid model combines a ResNet-34 branch for local texture and boundary information with a Swin-Tiny Transformer for global anatomi- cal context. A segmentation-guided classification mechanism further uses tumor localization information to support MIBC prediction. We also investigate several augmentation strategies under both centralized and federated training to improve robustness to multi-center variability. Ex- periments on the FedBCa dataset show that the Swin Hybrid provides the best overall balance between segmentation and classification among the evaluated architectures. Under federated training, Geo+Elastic aug- mentation achieved a DSC of 0.8100 and a patient-level AUC of 0.8931, yielding the highest combined score of 0.8474. These results demonstrate that joint segmentation and classification can be effectively performed across multiple institutions using federated training without centralizing patient data.

联邦学习医学图像多任务学习膀胱癌

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