arXiv:2609.04549cs.LG2026-09

用神经算子快速模拟神经元动力学,精度高且速度超快。

Fast Surrogate Modeling of Excitable and Oscillatory FitzHugh-Nagumo Dynamics with Parametric Neural Operators

  • 用参数化傅里叶神经算子建模神经元电压与恢复场,通过特征调制适配参数。
  • 在振荡区误差低于0.1%,推理速度比传统方法快近1000倍,可外推至训练范围外。
  • 在兴奋区准确捕捉放电阈值和传导速度规律,完整复现激发态分岔结构。

FitzHugh-Nagumo(FHN)系统是神经元电压动态的简化模型,体现激活-抑制机制,能描述单个动作电位及脑内节律性放电。探索其五维生理参数空间对神经调控与电压记录反演生物物理机制至关重要,但经典有限差分求解器使快速参数扫描代价高昂。本文训练参数条件化的傅里叶神经算子(FNOs),作为一维空间上电压场与恢复场的快速可微代理模型,通过特征逐维线性调制(FiLM)将参数向量λ = (D_u, D_v, a, b, τ)嵌入每层。通过一次分岔分析划分振荡(持续放电)与兴奋(动作电位传播)两种模式,分别训练一个算子。在振荡区,代理模型对两场相对L²误差均低于0.1%,推理速度比有限差分基线快近三个数量级,对参数空间具有均匀泛化能力,并在训练范围外实现低单百分数误差外推。在兴奋区,同一算子精确再现放电阈值与传导速度满足c ∝ √D_u的规律,完整复现行进脉冲与激发态分岔结构,而非仅平滑插值场。

原文摘要 · Abstract (English)

The FitzHugh-Nagumo (FHN) system serves as a simplified model of neuronal voltage dynamics, capturing the activator-inhibitor structure behind both isolated action potentials and the rhythmic spiking seen across the brain. Exploring its 5D physiological parameter space is important for neuromodulation and mapping voltage recordings back to biophysics, yet classical finite-difference solvers make rapid parameter sweeps expensive. We train parameter-conditioned Fourier Neural Operators (FNOs) as fast, differentiable surrogates for the FHN voltage and recovery fields on a one-dimensional spatial domain, conditioning each Fourier layer on the parameter vector $\lambda = (D_u, D_v, a, b, \tau)$ via feature-wise linear modulation (FiLM). We apply a single bifurcation analysis that delimits the two distinct regimes the model spans, oscillatory (tonic firing) and excitable (action-potential propagation), and we train one operator in each. In the oscillatory regime the surrogate attains sub-$0.1\%$ relative $L^2$ error on both fields, runs nearly three orders of magnitude faster than the finite-difference baseline, generalizes uniformly across the parameter space, and extrapolates to low single-digit percentage errors outside of the training bounds. In the excitable regime the same operator accurately reproduces the firing threshold and the $c \propto \sqrt{D_u}$ conduction-velocity law and replicates full traveling pulses, fully capturing the excitable bifurcation structure rather than just smoothly interpolating fields.

神经动力学神经算子快速建模分岔分析

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